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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHD1
All Species:
23.94
Human Site:
S56
Identified Species:
35.11
UniProt:
Q9BUP0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUP0
NP_079478.1
239
26928
S56
A
S
A
D
A
E
L
S
A
Q
L
S
R
R
L
Chimpanzee
Pan troglodytes
XP_001143163
390
43806
S207
A
S
A
D
A
E
L
S
A
Q
L
S
R
R
L
Rhesus Macaque
Macaca mulatta
Q5TM25
147
16701
L16
G
G
K
A
F
G
L
L
K
A
Q
Q
E
E
R
Dog
Lupus familis
XP_543290
141
15950
G10
T
Y
D
S
G
R
D
G
F
I
D
L
M
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4J1
240
26981
N57
A
S
A
D
S
E
L
N
L
K
L
S
R
R
L
Rat
Rattus norvegicus
Q4FZY0
239
26741
S55
G
S
A
D
D
E
L
S
A
K
L
L
R
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518105
170
19250
D39
E
Q
Y
D
A
G
R
D
G
F
I
D
L
M
E
Chicken
Gallus gallus
NP_001026943
238
26908
S55
A
S
A
G
A
E
L
S
A
K
L
A
R
R
H
Frog
Xenopus laevis
NP_001085773
231
26398
S47
S
N
A
D
S
E
L
S
A
K
L
N
R
R
Q
Zebra Danio
Brachydanio rerio
XP_683253
227
26230
T44
D
D
T
T
S
E
L
T
E
K
L
N
R
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ26
217
25068
M41
L
N
R
R
Q
E
I
M
E
S
Q
E
A
G
I
Honey Bee
Apis mellifera
XP_624640
195
22857
S44
Y
T
E
F
H
E
L
S
R
R
E
I
K
Q
Y
Nematode Worm
Caenorhab. elegans
O16305
149
16806
S18
A
E
F
K
E
A
F
S
L
F
D
K
D
G
D
Sea Urchin
Strong. purpuratus
XP_001176294
193
22506
T41
Y
T
E
F
K
E
F
T
R
K
Q
I
K
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQN4
166
18399
L35
K
D
G
S
L
T
Q
L
E
L
G
S
L
L
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P61859
149
16978
S18
S
E
F
K
E
A
F
S
L
F
D
K
D
G
D
Conservation
Percent
Protein Identity:
100
61.2
23.8
53.1
N.A.
81.2
65.6
N.A.
51.4
74.4
69.4
63.5
N.A.
48.5
47.7
21.3
50.2
Protein Similarity:
100
61.2
38.4
57.7
N.A.
87.9
78.6
N.A.
61
84
83.2
80.7
N.A.
59.4
61.9
38.4
61.5
P-Site Identity:
100
100
6.6
6.6
N.A.
73.3
66.6
N.A.
13.3
73.3
60
40
N.A.
6.6
20
13.3
6.6
P-Site Similarity:
100
100
6.6
6.6
N.A.
93.3
73.3
N.A.
20
86.6
93.3
66.6
N.A.
26.6
46.6
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
20.9
Protein Similarity:
N.A.
N.A.
N.A.
37.2
N.A.
38.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
32
0
38
7
25
13
0
0
32
7
0
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
13
7
38
7
0
7
7
0
0
19
7
13
0
13
% D
% Glu:
7
13
13
0
13
63
0
0
19
0
7
7
7
19
7
% E
% Phe:
0
0
13
13
7
0
19
0
7
19
0
0
0
0
7
% F
% Gly:
13
7
7
7
7
13
0
7
7
0
7
0
0
19
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
7
0
0
7
7
13
0
0
7
% I
% Lys:
7
0
7
13
7
0
0
0
7
38
0
13
13
0
0
% K
% Leu:
7
0
0
0
7
0
57
13
19
7
44
13
13
7
32
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
7
7
0
% M
% Asn:
0
13
0
0
0
0
0
7
0
0
0
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
7
0
7
0
0
13
19
7
0
7
7
% Q
% Arg:
0
0
7
7
0
7
7
0
13
7
0
0
44
44
13
% R
% Ser:
13
32
0
13
19
0
0
50
0
7
0
25
0
0
0
% S
% Thr:
7
13
7
7
0
7
0
13
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _