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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFHD1 All Species: 31.52
Human Site: T127 Identified Species: 46.22
UniProt: Q9BUP0 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BUP0 NP_079478.1 239 26928 T127 E K L G A P Q T H L G L K S M
Chimpanzee Pan troglodytes XP_001143163 390 43806 T278 E K L G A P Q T H L G L K S M
Rhesus Macaque Macaca mulatta Q5TM25 147 16701 K71 D I D I M S L K R M L E K L G
Dog Lupus familis XP_543290 141 15950 L65 H K A A A G E L E E D S G L M
Cat Felis silvestris
Mouse Mus musculus Q9D4J1 240 26981 T128 E K L G A P Q T H L G L K S M
Rat Rattus norvegicus Q4FZY0 239 26741 T128 E K L G A P Q T H L G L K S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518105 170 19250 E94 F H K A A A G E L Q E D S G L
Chicken Gallus gallus NP_001026943 238 26908 T126 E K L G A P Q T H L G L K N M
Frog Xenopus laevis NP_001085773 231 26398 T119 E K L G A P Q T H L G L K N M
Zebra Danio Brachydanio rerio XP_683253 227 26230 T115 E K L G A P Q T H L G L K N M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJ26 217 25068 T106 E K L G A P Q T H L G L K Q M
Honey Bee Apis mellifera XP_624640 195 22857 E106 D G R I S F R E F L L I Y R K
Nematode Worm Caenorhab. elegans O16305 149 16806 M73 F P E F L T M M A R K M K D T
Sea Urchin Strong. purpuratus XP_001176294 193 22506 D97 E A D E D L D D M I S F R E F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LQN4 166 18399 P90 S P A K R T T P Y T E E Q L L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P61859 149 16978 M73 F P E F L T M M A R K M K D T
Conservation
Percent
Protein Identity: 100 61.2 23.8 53.1 N.A. 81.2 65.6 N.A. 51.4 74.4 69.4 63.5 N.A. 48.5 47.7 21.3 50.2
Protein Similarity: 100 61.2 38.4 57.7 N.A. 87.9 78.6 N.A. 61 84 83.2 80.7 N.A. 59.4 61.9 38.4 61.5
P-Site Identity: 100 100 6.6 20 N.A. 100 100 N.A. 6.6 93.3 93.3 93.3 N.A. 93.3 6.6 6.6 6.6
P-Site Similarity: 100 100 20 26.6 N.A. 100 100 N.A. 13.3 100 100 100 N.A. 93.3 33.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 20.9 N.A. 20.9
Protein Similarity: N.A. N.A. N.A. 37.2 N.A. 38.9
P-Site Identity: N.A. N.A. N.A. 0 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 20 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 13 13 63 7 0 0 13 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 13 0 7 0 7 7 0 0 7 7 0 13 0 % D
% Glu: 57 0 13 7 0 0 7 13 7 7 13 13 0 7 0 % E
% Phe: 19 0 0 13 0 7 0 0 7 0 0 7 0 0 7 % F
% Gly: 0 7 0 50 0 7 7 0 0 0 50 0 7 7 7 % G
% His: 7 7 0 0 0 0 0 0 50 0 0 0 0 0 0 % H
% Ile: 0 7 0 13 0 0 0 0 0 7 0 7 0 0 0 % I
% Lys: 0 57 7 7 0 0 0 7 0 0 13 0 69 0 7 % K
% Leu: 0 0 50 0 13 7 7 7 7 57 13 50 0 19 13 % L
% Met: 0 0 0 0 7 0 13 13 7 7 0 13 0 0 57 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % N
% Pro: 0 19 0 0 0 50 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 50 0 0 7 0 0 7 7 0 % Q
% Arg: 0 0 7 0 7 0 7 0 7 13 0 0 7 7 0 % R
% Ser: 7 0 0 0 7 7 0 0 0 0 7 7 7 25 0 % S
% Thr: 0 0 0 0 0 19 7 50 0 7 0 0 0 0 13 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _