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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFHD1 All Species: 30
Human Site: T82 Identified Species: 44
UniProt: Q9BUP0 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BUP0 NP_079478.1 239 26928 T82 C R V F N P Y T E F P E F S R
Chimpanzee Pan troglodytes XP_001143163 390 43806 T233 C R V F N P Y T E F P E F S R
Rhesus Macaque Macaca mulatta Q5TM25 147 16701 K36 K Q F L D D P K Y S S D E D L
Dog Lupus familis XP_543290 141 15950 H30 K L G A P Q T H L G L K N M I
Cat Felis silvestris
Mouse Mus musculus Q9D4J1 240 26981 T83 S K V F N P Y T E F P E F S R
Rat Rattus norvegicus Q4FZY0 239 26741 T83 R R V F N P Y T E F K E F S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518105 170 19250 T59 E K L E A P Q T H L G L K N M
Chicken Gallus gallus NP_001026943 238 26908 T81 A A V F N P Y T E F K E F S R
Frog Xenopus laevis NP_001085773 231 26398 T74 G K V F N P Y T E F K E F S R
Zebra Danio Brachydanio rerio XP_683253 227 26230 T70 M K V F N P Y T E F K E F S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJ26 217 25068 T61 Y K V V N V Y T D F P E F S R
Honey Bee Apis mellifera XP_624640 195 22857 F65 F D D G H D G F L D L S E L K
Nematode Worm Caenorhab. elegans O16305 149 16806 R38 K E L G T V M R S L G Q N P T
Sea Urchin Strong. purpuratus XP_001176294 193 22506 F62 Y D T G G D N F I D M M E L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LQN4 166 18399 T55 P S P D Q F E T L I D K A D T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P61859 149 16978 R38 K E L G T V M R S L G Q N P S
Conservation
Percent
Protein Identity: 100 61.2 23.8 53.1 N.A. 81.2 65.6 N.A. 51.4 74.4 69.4 63.5 N.A. 48.5 47.7 21.3 50.2
Protein Similarity: 100 61.2 38.4 57.7 N.A. 87.9 78.6 N.A. 61 84 83.2 80.7 N.A. 59.4 61.9 38.4 61.5
P-Site Identity: 100 100 0 0 N.A. 86.6 86.6 N.A. 13.3 80 80 80 N.A. 66.6 0 0 0
P-Site Similarity: 100 100 20 6.6 N.A. 93.3 86.6 N.A. 33.3 80 86.6 86.6 N.A. 80 13.3 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 20.9 N.A. 20.9
Protein Similarity: N.A. N.A. N.A. 37.2 N.A. 38.9
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 0
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 7 7 0 0 0 0 0 0 0 7 0 0 % A
% Cys: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 13 7 7 7 19 0 0 7 13 7 7 0 13 0 % D
% Glu: 7 13 0 7 0 0 7 0 44 0 0 50 19 0 0 % E
% Phe: 7 0 7 44 0 7 0 13 0 50 0 0 50 0 0 % F
% Gly: 7 0 7 25 7 0 7 0 0 7 19 0 0 0 0 % G
% His: 0 0 0 0 7 0 0 7 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 7 % I
% Lys: 25 32 0 0 0 0 0 7 0 0 25 13 7 0 13 % K
% Leu: 0 7 19 7 0 0 0 0 19 19 13 7 0 13 7 % L
% Met: 7 0 0 0 0 0 13 0 0 0 7 7 0 7 7 % M
% Asn: 0 0 0 0 50 0 7 0 0 0 0 0 19 7 0 % N
% Pro: 7 0 7 0 7 50 7 0 0 0 25 0 0 13 0 % P
% Gln: 0 7 0 0 7 7 7 0 0 0 0 13 0 0 0 % Q
% Arg: 7 19 0 0 0 0 0 13 0 0 0 0 0 0 50 % R
% Ser: 7 7 0 0 0 0 0 0 13 7 7 7 0 50 7 % S
% Thr: 0 0 7 0 13 0 7 63 0 0 0 0 0 0 13 % T
% Val: 0 0 50 7 0 19 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 0 0 0 0 50 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _