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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WRAP53 All Species: 13.64
Human Site: T278 Identified Species: 30
UniProt: Q9BUR4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BUR4 NP_001137462.1 548 59309 T278 Y N H L D E L T A A H S L C F
Chimpanzee Pan troglodytes XP_001172037 548 59196 T278 Y N H L D E L T A A H S L C F
Rhesus Macaque Macaca mulatta XP_001110427 548 59348 T278 Y N H L D E L T A A H S L C F
Dog Lupus familis XP_849837 562 60347 Y279 S S E P D T S Y V A S S S R E
Cat Felis silvestris
Mouse Mus musculus Q8VC51 532 58133 F269 T A A H S L C F S P D G S Q L
Rat Rattus norvegicus Q5XII5 532 58177 F269 T A A H S L C F S P D G S Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002662853 534 59599 H271 L D E L T A A H S L C F S P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608997 543 60479 D277 I H M W D A F D G S L R C S Y
Honey Bee Apis mellifera XP_395306 368 42139 C105 G G L I Y D T C W Y P F M N S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795962 610 68301 S299 I N S V D E L S T P H S L C F
Poplar Tree Populus trichocarpa XP_002316658 374 41889 V111 A S D P V S C V F A T T T R D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.9 72.2 N.A. 78 78.2 N.A. N.A. N.A. N.A. 47.2 N.A. 31.9 30.2 N.A. 36
Protein Similarity: 100 99.4 97.6 77 N.A. 83.3 83.7 N.A. N.A. N.A. N.A. 61.8 N.A. 47.4 42.3 N.A. 54.2
P-Site Identity: 100 100 100 20 N.A. 0 0 N.A. N.A. N.A. N.A. 6.6 N.A. 6.6 0 N.A. 60
P-Site Similarity: 100 100 100 26.6 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 20 N.A. 26.6 20 N.A. 73.3
Percent
Protein Identity: 29.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 45.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 19 19 0 0 19 10 0 28 46 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 28 10 0 0 10 0 10 37 0 % C
% Asp: 0 10 10 0 55 10 0 10 0 0 19 0 0 0 19 % D
% Glu: 0 0 19 0 0 37 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 10 19 10 0 0 19 0 0 37 % F
% Gly: 10 10 0 0 0 0 0 0 10 0 0 19 0 0 0 % G
% His: 0 10 28 19 0 0 0 10 0 0 37 0 0 0 0 % H
% Ile: 19 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 37 0 19 37 0 0 10 10 0 37 0 19 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 37 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 19 0 0 0 0 0 28 10 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 19 0 % R
% Ser: 10 19 10 0 19 10 10 10 28 10 10 46 37 10 10 % S
% Thr: 19 0 0 0 10 10 10 28 10 0 10 10 10 0 0 % T
% Val: 0 0 0 10 10 0 0 10 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 28 0 0 0 10 0 0 10 0 10 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _