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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C1orf50
All Species:
13.03
Human Site:
S174
Identified Species:
23.89
UniProt:
Q9BV19
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV19
NP_077002.2
199
21877
S174
E
K
Q
D
A
K
I
S
M
M
D
T
L
L
S
Chimpanzee
Pan troglodytes
XP_513369
199
21888
S174
E
K
Q
D
A
K
I
S
M
M
D
T
L
L
S
Rhesus Macaque
Macaca mulatta
XP_001089238
199
21878
G174
E
K
Q
D
A
K
I
G
M
M
D
K
L
L
S
Dog
Lupus familis
XP_539558
258
27593
N229
E
K
H
D
A
K
I
N
I
V
D
K
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5EBG8
199
21844
G174
E
K
Q
D
A
K
I
G
M
M
D
K
L
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511886
154
17449
S129
E
K
R
E
A
E
I
S
M
V
E
K
L
L
S
Chicken
Gallus gallus
XP_417656
179
19519
N154
E
R
R
D
A
E
M
N
I
L
D
K
L
L
S
Frog
Xenopus laevis
Q5PQ76
184
20927
S159
E
K
R
D
A
E
I
S
I
I
D
K
L
L
N
Zebra Danio
Brachydanio rerio
Q502G5
189
21381
G164
E
K
R
D
A
E
I
G
I
M
D
K
L
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724152
182
21010
K155
K
E
Q
D
E
K
L
K
W
A
E
Q
C
M
L
Honey Bee
Apis mellifera
XP_397054
181
20800
I157
I
D
K
K
N
K
E
I
T
M
L
A
N
L
W
Nematode Worm
Caenorhab. elegans
Q09227
186
21535
G156
D
R
S
W
T
P
V
G
E
M
D
R
K
D
E
Sea Urchin
Strong. purpuratus
XP_001191335
197
22284
A154
P
K
R
S
E
E
I
A
I
I
D
K
L
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.9
67
N.A.
84.4
N.A.
N.A.
57.7
67.3
65.3
64.8
N.A.
35.6
38.1
33.6
52.2
Protein Similarity:
100
99.5
96.9
70.9
N.A.
87.9
N.A.
N.A.
69.8
78.3
78.8
77.8
N.A.
55.2
59.7
56.2
68.3
P-Site Identity:
100
100
86.6
66.6
N.A.
86.6
N.A.
N.A.
60
46.6
60
60
N.A.
20
20
13.3
40
P-Site Similarity:
100
100
86.6
86.6
N.A.
86.6
N.A.
N.A.
93.3
93.3
93.3
86.6
N.A.
53.3
26.6
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
70
0
0
8
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
8
0
70
0
0
0
0
0
0
77
0
0
8
0
% D
% Glu:
70
8
0
8
16
39
8
0
8
0
16
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
70
8
39
16
0
0
0
0
0
% I
% Lys:
8
70
8
8
0
54
0
8
0
0
0
62
8
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
8
8
0
77
85
8
% L
% Met:
0
0
0
0
0
0
8
0
39
54
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
0
0
16
0
0
0
0
8
0
16
% N
% Pro:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
39
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
16
39
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
8
8
0
0
0
31
0
0
0
0
0
0
62
% S
% Thr:
0
0
0
0
8
0
0
0
8
0
0
16
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _