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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRI1 All Species: 6.06
Human Site: S358 Identified Species: 9.52
UniProt: Q9BV20 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV20 NP_001026897.1 369 39150 S358 T A L T T T I S S R D G T L D
Chimpanzee Pan troglodytes XP_001171000 369 39131 S358 T A L T T T I S S R D G T L D
Rhesus Macaque Macaca mulatta XP_001111047 356 37822 C344 Q D G V G S G C H L A P E L D
Dog Lupus familis XP_542030 358 37589 G342 G G I I T E L G V F A P E D L
Cat Felis silvestris
Mouse Mus musculus Q9CQT1 369 39392 F358 G A L S A S V F S E G Q T L D
Rat Rattus norvegicus Q5HZE4 369 39569 F358 A A L S A T I F S E G Q T L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510432 347 36763 F324 A S L T S V V F S E G F G R V
Chicken Gallus gallus
Frog Xenopus laevis Q4FZP2 354 38121 V340 G I I T E R G V F K P E E L K
Zebra Danio Brachydanio rerio NP_001104708 353 37962 Q343 V F L P S E L Q A A L T G R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651868 364 39090 E353 R G V F K P A E L K E A I T K
Honey Bee Apis mellifera XP_392553 355 39215 V340 G I I T E V G V Y R P Q D L L
Nematode Worm Caenorhab. elegans Q93169 366 40843 G353 T K I L T D F G N W P P E M L
Sea Urchin Strong. purpuratus XP_001199953 312 33976 T302 E R D E S E L T K I N G M Q I
Poplar Tree Populus trichocarpa XP_002308521 384 40564 N372 F D I K D F I N R L S A S A L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06489 411 45002 I391 H E L I D G I I T E E G V F T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 85.6 89.4 N.A. 85.9 86.4 N.A. 70.7 N.A. 65.8 66.9 N.A. 58.8 57.1 43.9 51.2
Protein Similarity: 100 98.9 88.6 92.6 N.A. 90.5 90.2 N.A. 80.7 N.A. 78.5 79.1 N.A. 73.1 71.2 60.7 63.9
P-Site Identity: 100 100 13.3 6.6 N.A. 40 53.3 N.A. 20 N.A. 13.3 6.6 N.A. 0 20 13.3 6.6
P-Site Similarity: 100 100 20 20 N.A. 60 60 N.A. 40 N.A. 26.6 26.6 N.A. 20 26.6 33.3 33.3
Percent
Protein Identity: 51 N.A. N.A. N.A. 37.2 N.A.
Protein Similarity: 63.8 N.A. N.A. N.A. 54.9 N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 27 0 0 14 0 7 0 7 7 14 14 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 14 7 0 14 7 0 0 0 0 14 0 7 7 34 % D
% Glu: 7 7 0 7 14 20 0 7 0 27 14 7 27 0 0 % E
% Phe: 7 7 0 7 0 7 7 20 7 7 0 7 0 7 0 % F
% Gly: 27 14 7 0 7 7 20 14 0 0 20 27 14 0 0 % G
% His: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 14 34 14 0 0 34 7 0 7 0 0 7 0 7 % I
% Lys: 0 7 0 7 7 0 0 0 7 14 0 0 0 0 14 % K
% Leu: 0 0 47 7 0 0 20 0 7 14 7 0 0 47 34 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % M
% Asn: 0 0 0 0 0 0 0 7 7 0 7 0 0 0 0 % N
% Pro: 0 0 0 7 0 7 0 0 0 0 20 20 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 7 0 0 0 20 0 7 0 % Q
% Arg: 7 7 0 0 0 7 0 0 7 20 0 0 0 14 0 % R
% Ser: 0 7 0 14 20 14 0 14 34 0 7 0 7 0 0 % S
% Thr: 20 0 0 34 27 20 0 7 7 0 0 7 27 7 7 % T
% Val: 7 0 7 7 0 14 14 14 7 0 0 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _