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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRI1 All Species: 22.12
Human Site: T291 Identified Species: 34.76
UniProt: Q9BV20 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV20 NP_001026897.1 369 39150 T291 S C D L R L E T G K E I I I E
Chimpanzee Pan troglodytes XP_001171000 369 39131 T291 S C D L R L E T G K E I I I E
Rhesus Macaque Macaca mulatta XP_001111047 356 37822 S282 P F Y V A A P S S S C D L R L
Dog Lupus familis XP_542030 358 37589 P281 I P F Y V A A P S S S C D L R
Cat Felis silvestris
Mouse Mus musculus Q9CQT1 369 39392 T291 S C D L H L E T G K E I V I E
Rat Rattus norvegicus Q5HZE4 369 39569 T291 S C D L R L E T G K E I V I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510432 347 36763 V262 L P S G R E I V I E E R P E R
Chicken Gallus gallus
Frog Xenopus laevis Q4FZP2 354 38121 S280 P F Y V A A P S T S C D L S L
Zebra Danio Brachydanio rerio NP_001104708 353 37962 S281 P S T S C D L S L E S G R D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651868 364 39090 D292 A A P L T S I D L A I P G G D
Honey Bee Apis mellifera XP_392553 355 39215 R280 P F Y V A A P R T S I D F S I
Nematode Worm Caenorhab. elegans Q93169 366 40843 P293 I N F Y P V V P F T T I N K N
Sea Urchin Strong. purpuratus XP_001199953 312 33976 G242 G V T A V V V G A D R V V A N
Poplar Tree Populus trichocarpa XP_002308521 384 40564 S302 S F D S S L S S G K E I I I E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06489 411 45002 T323 T I D N V T E T G D D I I V E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 85.6 89.4 N.A. 85.9 86.4 N.A. 70.7 N.A. 65.8 66.9 N.A. 58.8 57.1 43.9 51.2
Protein Similarity: 100 98.9 88.6 92.6 N.A. 90.5 90.2 N.A. 80.7 N.A. 78.5 79.1 N.A. 73.1 71.2 60.7 63.9
P-Site Identity: 100 100 0 0 N.A. 86.6 93.3 N.A. 13.3 N.A. 0 0 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 100 20 6.6 N.A. 93.3 100 N.A. 20 N.A. 20 13.3 N.A. 20 6.6 13.3 20
Percent
Protein Identity: 51 N.A. N.A. N.A. 37.2 N.A.
Protein Similarity: 63.8 N.A. N.A. N.A. 54.9 N.A.
P-Site Identity: 66.6 N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: 73.3 N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 7 20 27 7 0 7 7 0 0 0 7 0 % A
% Cys: 0 27 0 0 7 0 0 0 0 0 14 7 0 0 0 % C
% Asp: 0 0 40 0 0 7 0 7 0 14 7 20 7 7 7 % D
% Glu: 0 0 0 0 0 7 34 0 0 14 40 0 0 7 40 % E
% Phe: 0 27 14 0 0 0 0 0 7 0 0 0 7 0 0 % F
% Gly: 7 0 0 7 0 0 0 7 40 0 0 7 7 7 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 14 7 0 0 0 0 14 0 7 0 14 47 27 34 14 % I
% Lys: 0 0 0 0 0 0 0 0 0 34 0 0 0 7 0 % K
% Leu: 7 0 0 34 0 34 7 0 14 0 0 0 14 7 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 0 0 0 0 0 0 0 7 0 14 % N
% Pro: 27 14 7 0 7 0 20 14 0 0 0 7 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 27 0 0 7 0 0 7 7 7 7 14 % R
% Ser: 34 7 7 14 7 7 7 27 14 27 14 0 0 14 0 % S
% Thr: 7 0 14 0 7 7 0 34 14 7 7 0 0 0 0 % T
% Val: 0 7 0 20 20 14 14 7 0 0 0 7 20 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 20 14 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _