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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRI1 All Species: 36.36
Human Site: Y27 Identified Species: 57.14
UniProt: Q9BV20 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV20 NP_001026897.1 369 39150 Y27 L L P K Q S R Y E A V G S V H
Chimpanzee Pan troglodytes XP_001171000 369 39131 Y27 L L P Q Q S R Y E A V G S V H
Rhesus Macaque Macaca mulatta XP_001111047 356 37822 Y27 L L P Q Q S R Y E A V G S V R
Dog Lupus familis XP_542030 358 37589 Y27 L L P Q R S R Y E P V G S V R
Cat Felis silvestris
Mouse Mus musculus Q9CQT1 369 39392 Y27 Q L P E H C H Y E A L S S V Q
Rat Rattus norvegicus Q5HZE4 369 39569 Y27 Q L P E H C H Y E T L S S V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510432 347 36763 L29 C L S L A V E L R A G G G G P
Chicken Gallus gallus
Frog Xenopus laevis Q4FZP2 354 38121 Y27 L L P H K S E Y E P V T G V Q
Zebra Danio Brachydanio rerio NP_001104708 353 37962 Y27 L L P R E T V Y D E I R S V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651868 364 39090 Y27 L L P G Q S K Y V V V R G V E
Honey Bee Apis mellifera XP_392553 355 39215 Y27 L L P A M S R Y I S V R G V E
Nematode Worm Caenorhab. elegans Q93169 366 40843 Y49 L L P H E F K Y I P V E G V S
Sea Urchin Strong. purpuratus XP_001199953 312 33976 G11 K A I R Y K R G S L E I L N Q
Poplar Tree Populus trichocarpa XP_002308521 384 40564 Y39 K L P L E T T Y L D I K D A S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06489 411 45002 Y32 L L P Y T T K Y V P I H T I D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 85.6 89.4 N.A. 85.9 86.4 N.A. 70.7 N.A. 65.8 66.9 N.A. 58.8 57.1 43.9 51.2
Protein Similarity: 100 98.9 88.6 92.6 N.A. 90.5 90.2 N.A. 80.7 N.A. 78.5 79.1 N.A. 73.1 71.2 60.7 63.9
P-Site Identity: 100 93.3 86.6 73.3 N.A. 46.6 40 N.A. 20 N.A. 53.3 40 N.A. 53.3 53.3 40 6.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 60 53.3 N.A. 20 N.A. 60 73.3 N.A. 60 60 53.3 13.3
Percent
Protein Identity: 51 N.A. N.A. N.A. 37.2 N.A.
Protein Similarity: 63.8 N.A. N.A. N.A. 54.9 N.A.
P-Site Identity: 20 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 40 N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 7 0 0 0 0 34 0 0 0 7 0 % A
% Cys: 7 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 7 7 0 0 7 0 7 % D
% Glu: 0 0 0 14 20 0 14 0 47 7 7 7 0 0 14 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 7 0 0 7 34 34 7 0 % G
% His: 0 0 0 14 14 0 14 0 0 0 0 7 0 0 14 % H
% Ile: 0 0 7 0 0 0 0 0 14 0 20 7 0 7 0 % I
% Lys: 14 0 0 7 7 7 20 0 0 0 0 7 0 0 0 % K
% Leu: 67 94 0 14 0 0 0 7 7 7 14 0 7 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % N
% Pro: 0 0 87 0 0 0 0 0 0 27 0 0 0 0 7 % P
% Gln: 14 0 0 20 27 0 0 0 0 0 0 0 0 0 27 % Q
% Arg: 0 0 0 14 7 0 40 0 7 0 0 20 0 0 20 % R
% Ser: 0 0 7 0 0 47 0 0 7 7 0 14 47 0 14 % S
% Thr: 0 0 0 0 7 20 7 0 0 7 0 7 7 0 0 % T
% Val: 0 0 0 0 0 7 7 0 14 7 54 0 0 74 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 7 0 0 87 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _