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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A23 All Species: 37.27
Human Site: S371 Identified Species: 63.08
UniProt: Q9BV35 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV35 NP_077008.2 468 52378 S371 L Q Q Y S H D S A D P G I L V
Chimpanzee Pan troglodytes XP_524071 785 87514 S552 L Q Q Y S H D S A D P G I L V
Rhesus Macaque Macaca mulatta XP_001088378 468 52373 S371 L Q Q Y S H D S A D P G I L V
Dog Lupus familis XP_542138 468 52473 S371 L Q Q Y S R D S A D P G I L V
Cat Felis silvestris
Mouse Mus musculus Q6GQS1 467 52478 S370 L Q Q Y S H E S A N P G I L V
Rat Rattus norvegicus Q8K3P6 469 52677 S372 L Q R Y A V N S A D P G V F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519699 472 53241 S375 L Q Q Y S Q N S A D P G I L V
Chicken Gallus gallus XP_422180 475 52468 Y376 K T T W L E H Y A S S S A N P
Frog Xenopus laevis Q7ZYD5 514 56789 S417 L Q R Y A T S S A D P G V F V
Zebra Danio Brachydanio rerio Q66L49 477 53337 T381 L S H Y A K D T A N P G V L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20799 588 66319 S437 V R Y Y E T N S S E P G V L A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P29518 436 46609 A340 G S A A G A I A S S A T F P L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65023 381 41798 V285 Q S S L L T A V L S A G I A T
Baker's Yeast Sacchar. cerevisiae P48233 545 61252 L443 I A K Q A K T L N L P Q D Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.3 99.7 95 N.A. 93.5 63.1 N.A. 87.7 62.1 61 62.8 N.A. N.A. N.A. 40.1 N.A.
Protein Similarity: 100 58.2 100 97.2 N.A. 97 75.6 N.A. 93.2 78.5 73.1 79.2 N.A. N.A. N.A. 57.9 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 86.6 60 N.A. 86.6 6.6 60 53.3 N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 86.6 N.A. 93.3 13.3 80 80 N.A. N.A. N.A. 73.3 N.A.
Percent
Protein Identity: N.A. 27.1 N.A. 22.4 28.9 N.A.
Protein Similarity: N.A. 45.3 N.A. 39.3 48.2 N.A.
P-Site Identity: N.A. 0 N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. 20 N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 8 29 8 8 8 72 0 15 0 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 36 0 0 50 0 0 8 0 0 % D
% Glu: 0 0 0 0 8 8 8 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 15 0 % F
% Gly: 8 0 0 0 8 0 0 0 0 0 0 79 0 0 0 % G
% His: 0 0 8 0 0 29 8 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 0 0 0 0 50 0 0 % I
% Lys: 8 0 8 0 0 15 0 0 0 0 0 0 0 0 0 % K
% Leu: 65 0 0 8 15 0 0 8 8 8 0 0 0 58 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 22 0 8 15 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 79 0 0 8 8 % P
% Gln: 8 58 43 8 0 8 0 0 0 0 0 8 0 8 0 % Q
% Arg: 0 8 15 0 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 22 8 0 43 0 8 65 15 22 8 8 0 0 0 % S
% Thr: 0 8 8 0 0 22 8 8 0 0 0 8 0 0 8 % T
% Val: 8 0 0 0 0 8 0 8 0 0 0 0 29 0 72 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 72 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _