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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLPH
All Species:
6.97
Human Site:
S588
Identified Species:
19.17
UniProt:
Q9BV36
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV36
NP_001035932.1
600
65949
S588
N
A
R
K
G
M
A
S
H
T
F
A
K
P
V
Chimpanzee
Pan troglodytes
XP_516180
588
64390
S576
N
A
R
K
G
M
A
S
H
T
F
A
K
P
V
Rhesus Macaque
Macaca mulatta
XP_001115652
794
88464
T754
K
I
E
T
S
S
V
T
T
I
K
T
F
N
R
Dog
Lupus familis
XP_542722
939
103906
V860
L
L
G
E
E
K
E
V
L
W
Q
F
W
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91V27
590
65034
R578
N
G
R
R
G
T
A
R
H
I
F
A
K
P
V
Rat
Rattus norvegicus
Q7TNY7
856
94966
S838
S
T
N
R
P
T
A
S
T
S
N
T
K
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512824
487
54297
Y476
G
L
V
G
D
G
V
Y
R
F
G
R
S
E
R
Chicken
Gallus gallus
NP_001108552
683
77108
E671
N
G
K
N
R
R
V
E
R
L
F
A
K
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073147
503
58322
D492
S
A
K
G
L
S
I
D
K
A
K
K
K
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
26.3
26.4
N.A.
64.3
23.9
N.A.
31.6
45.9
N.A.
31
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
89.1
41
40.8
N.A.
73.5
38.5
N.A.
44.5
59
N.A.
50.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
66.6
20
N.A.
0
40
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
13.3
N.A.
73.3
46.6
N.A.
0
46.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
0
0
45
0
0
12
0
45
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
12
0
0
0
0
0
12
0
% D
% Glu:
0
0
12
12
12
0
12
12
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
45
12
12
0
0
% F
% Gly:
12
23
12
23
34
12
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
34
0
0
0
0
12
0
% H
% Ile:
0
12
0
0
0
0
12
0
0
23
0
0
0
0
0
% I
% Lys:
12
0
23
23
0
12
0
0
12
0
23
12
67
0
0
% K
% Leu:
12
23
0
0
12
0
0
0
12
12
0
0
0
0
23
% L
% Met:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% M
% Asn:
45
0
12
12
0
0
0
0
0
0
12
0
0
12
12
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
0
0
45
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
34
23
12
12
0
12
23
0
0
12
0
0
23
% R
% Ser:
23
0
0
0
12
23
0
34
0
12
0
0
12
0
0
% S
% Thr:
0
12
0
12
0
23
0
12
23
23
0
23
0
0
0
% T
% Val:
0
0
12
0
0
0
34
12
0
0
0
0
0
12
45
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _