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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR18 All Species: 25.15
Human Site: S138 Identified Species: 46.11
UniProt: Q9BV38 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV38 NP_077005.2 432 47405 S138 G D S S H F I S G G K D C L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093021 438 48180 S144 G D S S H F I S G G K D C L V
Dog Lupus familis XP_855191 366 40302 P92 C S V L Q V D P S R T P A P R
Cat Felis silvestris
Mouse Mus musculus Q4VBE8 431 47193 S138 G D G S H F V S A G K D C L A
Rat Rattus norvegicus Q499N3 431 47207 S138 G D G S H F V S A G K D C L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026107 398 43477 L124 L N R H Y Q D L T C L C F T D
Frog Xenopus laevis NP_001089507 428 47004 S138 D D G S H I V S G A K D S L V
Zebra Danio Brachydanio rerio NP_001005206 431 47137 S138 D D S S H F V S G G K D N L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569954 506 55930 S140 D N G E H F I S G G K D G A V
Honey Bee Apis mellifera XP_001121386 398 44798 Q124 R L L K N L S Q H Y Q T V S C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002327154 446 49129 S140 D S L L V S G S E D G S V R V
Maize Zea mays NP_001146650 428 47186 V141 G L Y D Y L L V S G S E D G T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_190487 438 48131 S137 G D D S L L V S G S Q D G S I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 90.6 76.3 N.A. 83.3 83 N.A. N.A. 66.9 64.1 60.8 N.A. 29.8 34.9 N.A. N.A.
Protein Similarity: 100 N.A. 92.9 79.8 N.A. 90.9 91.1 N.A. N.A. 78.2 78 79.8 N.A. 50 52.3 N.A. N.A.
P-Site Identity: 100 N.A. 100 0 N.A. 73.3 80 N.A. N.A. 0 60 73.3 N.A. 60 0 N.A. N.A.
P-Site Similarity: 100 N.A. 100 0 N.A. 80 86.6 N.A. N.A. 13.3 66.6 80 N.A. 66.6 13.3 N.A. N.A.
Percent
Protein Identity: 26.6 28.7 N.A. 22.8 N.A. N.A.
Protein Similarity: 44.6 46.3 N.A. 44 N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. 40 N.A. N.A.
P-Site Similarity: 13.3 33.3 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 16 8 0 0 8 8 16 % A
% Cys: 8 0 0 0 0 0 0 0 0 8 0 8 31 0 8 % C
% Asp: 31 54 8 8 0 0 16 0 0 8 0 62 8 0 8 % D
% Glu: 0 0 0 8 0 0 0 0 8 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 47 0 0 0 0 0 0 8 0 0 % F
% Gly: 47 0 31 0 0 0 8 0 47 54 8 0 16 8 0 % G
% His: 0 0 0 8 54 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 24 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 54 0 0 0 0 % K
% Leu: 8 16 16 16 8 24 8 8 0 0 8 0 0 47 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 16 0 0 8 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 8 0 8 0 % P
% Gln: 0 0 0 0 8 8 0 8 0 0 16 0 0 0 0 % Q
% Arg: 8 0 8 0 0 0 0 0 0 8 0 0 0 8 8 % R
% Ser: 0 16 24 54 0 8 8 70 16 8 8 8 8 16 0 % S
% Thr: 0 0 0 0 0 0 0 0 8 0 8 8 0 8 8 % T
% Val: 0 0 8 0 8 8 39 8 0 0 0 0 16 0 47 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 16 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _