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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR18
All Species:
22.73
Human Site:
S276
Identified Species:
41.67
UniProt:
Q9BV38
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV38
NP_077005.2
432
47405
S276
R
N
Q
V
T
C
L
S
V
S
T
D
G
S
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093021
438
48180
S282
R
N
Q
V
T
C
L
S
V
S
T
D
G
S
V
Dog
Lupus familis
XP_855191
366
40302
T226
L
S
G
S
H
D
E
T
V
R
L
W
D
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q4VBE8
431
47193
S276
R
N
Q
V
T
C
L
S
V
S
T
D
G
S
V
Rat
Rattus norvegicus
Q499N3
431
47207
S276
R
N
Q
V
T
C
L
S
V
S
T
D
G
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026107
398
43477
E258
R
D
R
T
F
Q
T
E
R
E
N
G
K
I
F
Frog
Xenopus laevis
NP_001089507
428
47004
S274
R
N
Q
V
T
C
L
S
V
S
L
D
G
S
M
Zebra Danio
Brachydanio rerio
NP_001005206
431
47137
S276
R
N
L
V
T
C
L
S
V
S
M
D
G
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569954
506
55930
A282
G
K
A
I
T
C
L
A
L
N
I
S
A
T
T
Honey Bee
Apis mellifera
XP_001121386
398
44798
Q258
R
G
I
E
H
H
V
Q
I
R
K
D
G
N
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002327154
446
49129
A275
S
K
N
V
T
C
L
A
Y
S
T
N
G
N
V
Maize
Zea mays
NP_001146650
428
47186
A276
S
K
A
V
T
S
L
A
S
S
R
D
G
L
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190487
438
48131
I279
C
A
D
G
N
L
L
I
S
G
S
E
D
G
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90.6
76.3
N.A.
83.3
83
N.A.
N.A.
66.9
64.1
60.8
N.A.
29.8
34.9
N.A.
N.A.
Protein Similarity:
100
N.A.
92.9
79.8
N.A.
90.9
91.1
N.A.
N.A.
78.2
78
79.8
N.A.
50
52.3
N.A.
N.A.
P-Site Identity:
100
N.A.
100
6.6
N.A.
100
93.3
N.A.
N.A.
6.6
86.6
80
N.A.
20
20
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
20
N.A.
100
100
N.A.
N.A.
20
93.3
86.6
N.A.
53.3
40
N.A.
N.A.
Percent
Protein Identity:
26.6
28.7
N.A.
22.8
N.A.
N.A.
Protein Similarity:
44.6
46.3
N.A.
44
N.A.
N.A.
P-Site Identity:
53.3
40
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
73.3
53.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
0
0
0
0
24
0
0
0
0
8
0
0
% A
% Cys:
8
0
0
0
0
62
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
8
0
0
0
0
0
62
16
0
0
% D
% Glu:
0
0
0
8
0
0
8
8
0
8
0
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
8
8
8
0
0
0
0
0
8
0
8
70
8
0
% G
% His:
0
0
0
0
16
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
8
8
0
8
0
0
16
8
% I
% Lys:
0
24
0
0
0
0
0
0
0
0
8
0
8
0
0
% K
% Leu:
8
0
8
0
0
8
77
0
8
0
16
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
47
8
0
8
0
0
0
0
8
8
8
0
16
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
39
0
0
8
0
8
0
0
0
0
0
0
8
% Q
% Arg:
62
0
8
0
0
0
0
0
8
16
8
0
0
0
0
% R
% Ser:
16
8
0
8
0
8
0
47
16
62
8
8
0
39
8
% S
% Thr:
0
0
0
8
70
0
8
8
0
0
39
0
0
16
8
% T
% Val:
0
0
0
62
0
0
8
0
54
0
0
0
0
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _