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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR18 All Species: 16.67
Human Site: S333 Identified Species: 30.56
UniProt: Q9BV38 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV38 NP_077005.2 432 47405 S333 L S S D F R P S L P L P H F N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093021 438 48180 S339 L S S D F R P S L P L P H F N
Dog Lupus familis XP_855191 366 40302 G283 H L L G A E H G D E P H R G G
Cat Felis silvestris
Mouse Mus musculus Q4VBE8 431 47193 S333 L N P E F R P S L P L P H F N
Rat Rattus norvegicus Q499N3 431 47207 S333 L N P E F R P S L P L P H F N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026107 398 43477 N315 N H K G P V T N A F I V L A P
Frog Xenopus laevis NP_001089507 428 47004 S331 L R S E S K P S F P L P H F S
Zebra Danio Brachydanio rerio NP_001005206 431 47137 A333 F L S D S H P A V P L P R F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569954 506 55930 P339 F L P E H K Q P Q M F A D S L
Honey Bee Apis mellifera XP_001121386 398 44798 H315 Q I L R T I N H K G P I T A A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002327154 446 49129 N332 L N P R S L S N V Q A S S R R
Maize Zea mays NP_001146650 428 47186 L333 N L P P L Q P L R K V R S A N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_190487 438 48131 R336 T Q V S W K S R G A L I P P P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 90.6 76.3 N.A. 83.3 83 N.A. N.A. 66.9 64.1 60.8 N.A. 29.8 34.9 N.A. N.A.
Protein Similarity: 100 N.A. 92.9 79.8 N.A. 90.9 91.1 N.A. N.A. 78.2 78 79.8 N.A. 50 52.3 N.A. N.A.
P-Site Identity: 100 N.A. 100 0 N.A. 80 80 N.A. N.A. 0 60 46.6 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 N.A. 100 0 N.A. 93.3 93.3 N.A. N.A. 13.3 80 66.6 N.A. 13.3 0 N.A. N.A.
Percent
Protein Identity: 26.6 28.7 N.A. 22.8 N.A. N.A.
Protein Similarity: 44.6 46.3 N.A. 44 N.A. N.A.
P-Site Identity: 6.6 13.3 N.A. 6.6 N.A. N.A.
P-Site Similarity: 26.6 26.6 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 8 8 8 8 0 24 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 24 0 0 0 0 8 0 0 0 8 0 0 % D
% Glu: 0 0 0 31 0 8 0 0 0 8 0 0 0 0 0 % E
% Phe: 16 0 0 0 31 0 0 0 8 8 8 0 0 47 0 % F
% Gly: 0 0 0 16 0 0 0 8 8 8 0 0 0 8 8 % G
% His: 8 8 0 0 8 8 8 8 0 0 0 8 39 0 0 % H
% Ile: 0 8 0 0 0 8 0 0 0 0 8 16 0 0 0 % I
% Lys: 0 0 8 0 0 24 0 0 8 8 0 0 0 0 0 % K
% Leu: 47 31 16 0 8 8 0 8 31 0 54 0 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 16 24 0 0 0 0 8 16 0 0 0 0 0 0 39 % N
% Pro: 0 0 39 8 8 0 54 8 0 47 16 47 8 8 16 % P
% Gln: 8 8 0 0 0 8 8 0 8 8 0 0 0 0 0 % Q
% Arg: 0 8 0 16 0 31 0 8 8 0 0 8 16 8 8 % R
% Ser: 0 16 31 8 24 0 16 39 0 0 0 8 16 8 16 % S
% Thr: 8 0 0 0 8 0 8 0 0 0 0 0 8 0 0 % T
% Val: 0 0 8 0 0 8 0 0 16 0 8 8 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _