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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR18
All Species:
17.58
Human Site:
S423
Identified Species:
32.22
UniProt:
Q9BV38
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV38
NP_077005.2
432
47405
S423
N
R
D
L
F
D
F
S
T
R
F
I
T
R
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093021
438
48180
S429
N
R
D
L
F
D
F
S
T
R
F
I
T
R
P
Dog
Lupus familis
XP_855191
366
40302
T358
R
D
L
F
D
F
S
T
R
I
I
T
R
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q4VBE8
431
47193
S422
N
R
D
L
F
D
F
S
T
R
I
I
T
R
P
Rat
Rattus norvegicus
Q499N3
431
47207
S422
N
R
D
L
F
D
F
S
T
R
I
I
T
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026107
398
43477
R390
R
L
R
R
C
T
L
R
C
A
Q
R
G
K
R
Frog
Xenopus laevis
NP_001089507
428
47004
L417
V
R
K
I
N
K
D
L
F
D
F
S
A
R
I
Zebra Danio
Brachydanio rerio
NP_001005206
431
47137
S423
N
K
D
L
Y
E
F
S
T
Q
L
L
T
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569954
506
55930
A480
S
M
R
L
F
Q
I
A
F
K
Y
I
T
S
D
Honey Bee
Apis mellifera
XP_001121386
398
44798
G390
Y
S
H
F
W
S
R
G
F
I
Q
A
R
I
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002327154
446
49129
C432
Y
D
N
L
H
E
F
C
V
D
E
L
L
E
G
Maize
Zea mays
NP_001146650
428
47186
L419
D
L
F
V
H
E
V
L
H
Q
M
P
S
S
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190487
438
48131
L424
W
Q
K
N
Y
E
N
L
L
Q
V
V
M
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90.6
76.3
N.A.
83.3
83
N.A.
N.A.
66.9
64.1
60.8
N.A.
29.8
34.9
N.A.
N.A.
Protein Similarity:
100
N.A.
92.9
79.8
N.A.
90.9
91.1
N.A.
N.A.
78.2
78
79.8
N.A.
50
52.3
N.A.
N.A.
P-Site Identity:
100
N.A.
100
0
N.A.
93.3
93.3
N.A.
N.A.
0
20
53.3
N.A.
26.6
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
6.6
N.A.
93.3
93.3
N.A.
N.A.
6.6
26.6
93.3
N.A.
53.3
6.6
N.A.
N.A.
Percent
Protein Identity:
26.6
28.7
N.A.
22.8
N.A.
N.A.
Protein Similarity:
44.6
46.3
N.A.
44
N.A.
N.A.
P-Site Identity:
13.3
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
33.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
8
0
8
8
0
8
% A
% Cys:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
8
16
39
0
8
31
8
0
0
16
0
0
0
0
16
% D
% Glu:
0
0
0
0
0
31
0
0
0
0
8
0
0
16
8
% E
% Phe:
0
0
8
16
39
8
47
0
24
0
24
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% G
% His:
0
0
8
0
16
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
16
24
39
0
8
8
% I
% Lys:
0
8
16
0
0
8
0
0
0
8
0
0
0
16
0
% K
% Leu:
0
16
8
54
0
0
8
24
8
0
8
16
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
39
0
8
8
8
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
39
% P
% Gln:
0
8
0
0
0
8
0
0
0
24
16
0
0
0
0
% Q
% Arg:
16
39
16
8
0
0
8
8
8
31
0
8
16
39
16
% R
% Ser:
8
8
0
0
0
8
8
39
0
0
0
8
8
16
0
% S
% Thr:
0
0
0
0
0
8
0
8
39
0
0
8
47
0
0
% T
% Val:
8
0
0
8
0
0
8
0
8
0
8
8
0
0
0
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
16
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _