KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR18
All Species:
18.48
Human Site:
T246
Identified Species:
33.89
UniProt:
Q9BV38
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV38
NP_077005.2
432
47405
T246
I
F
Q
V
D
L
F
T
W
P
G
Q
R
E
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093021
438
48180
T252
I
F
Q
V
D
L
F
T
W
P
G
Q
R
E
R
Dog
Lupus familis
XP_855191
366
40302
R200
Q
D
N
G
K
V
F
R
G
H
R
N
Q
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q4VBE8
431
47193
S246
I
F
Q
V
D
L
C
S
W
P
G
L
R
E
H
Rat
Rattus norvegicus
Q499N3
431
47207
S246
I
F
Q
V
D
L
C
S
R
P
G
P
R
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026107
398
43477
C232
L
S
E
Y
H
M
F
C
G
G
M
D
G
S
I
Frog
Xenopus laevis
NP_001089507
428
47004
T246
I
Y
Q
V
D
L
Y
T
T
P
E
Q
R
E
R
Zebra Danio
Brachydanio rerio
NP_001005206
431
47137
S246
I
F
Q
V
S
L
C
S
T
S
L
S
R
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569954
506
55930
F248
S
D
G
K
V
F
V
F
N
M
E
N
A
P
R
Honey Bee
Apis mellifera
XP_001121386
398
44798
L232
M
N
I
R
E
S
D
L
F
V
G
C
T
D
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002327154
446
49129
A248
I
H
I
A
A
L
G
A
D
S
S
S
I
K
S
Maize
Zea mays
NP_001146650
428
47186
V249
I
Y
V
T
A
M
G
V
D
L
S
F
H
G
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190487
438
48131
I245
S
K
I
Y
I
G
A
I
N
A
T
S
E
Y
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90.6
76.3
N.A.
83.3
83
N.A.
N.A.
66.9
64.1
60.8
N.A.
29.8
34.9
N.A.
N.A.
Protein Similarity:
100
N.A.
92.9
79.8
N.A.
90.9
91.1
N.A.
N.A.
78.2
78
79.8
N.A.
50
52.3
N.A.
N.A.
P-Site Identity:
100
N.A.
100
6.6
N.A.
73.3
66.6
N.A.
N.A.
6.6
73.3
40
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
20
N.A.
80
80
N.A.
N.A.
26.6
86.6
60
N.A.
6.6
33.3
N.A.
N.A.
Percent
Protein Identity:
26.6
28.7
N.A.
22.8
N.A.
N.A.
Protein Similarity:
44.6
46.3
N.A.
44
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
26.6
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
16
0
8
8
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
24
8
0
0
0
8
0
0
0
% C
% Asp:
0
16
0
0
39
0
8
0
16
0
0
8
0
16
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
0
16
0
8
39
0
% E
% Phe:
0
39
0
0
0
8
31
8
8
0
0
8
0
0
0
% F
% Gly:
0
0
8
8
0
8
16
0
16
8
39
0
8
8
16
% G
% His:
0
8
0
0
8
0
0
0
0
8
0
0
8
0
8
% H
% Ile:
62
0
24
0
8
0
0
8
0
0
0
0
8
0
8
% I
% Lys:
0
8
0
8
8
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
8
0
0
0
0
54
0
8
0
8
8
8
0
0
0
% L
% Met:
8
0
0
0
0
16
0
0
0
8
8
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
16
0
0
16
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
39
0
8
0
8
0
% P
% Gln:
8
0
47
0
0
0
0
0
0
0
0
24
8
0
8
% Q
% Arg:
0
0
0
8
0
0
0
8
8
0
8
0
47
0
39
% R
% Ser:
16
8
0
0
8
8
0
24
0
16
16
24
0
8
8
% S
% Thr:
0
0
0
8
0
0
0
24
16
0
8
0
8
0
8
% T
% Val:
0
0
8
47
8
8
8
8
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% W
% Tyr:
0
16
0
16
0
0
8
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _