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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR18
All Species:
8.79
Human Site:
T358
Identified Species:
16.11
UniProt:
Q9BV38
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV38
NP_077005.2
432
47405
T358
E
P
R
H
G
G
L
T
L
R
L
G
L
H
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093021
438
48180
T364
E
P
R
H
G
G
L
T
L
R
L
G
L
H
Q
Dog
Lupus familis
XP_855191
366
40302
H298
F
T
L
R
L
G
L
H
Q
Q
G
S
E
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q4VBE8
431
47193
R358
E
A
Q
G
G
G
L
R
L
Q
L
G
L
H
L
Rat
Rattus norvegicus
Q499N3
431
47207
R358
E
A
Q
G
G
G
L
R
L
Q
L
G
L
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026107
398
43477
G330
A
N
M
L
N
P
D
G
K
P
S
V
P
L
P
Frog
Xenopus laevis
NP_001089507
428
47004
I356
G
P
E
S
G
G
V
I
L
R
L
G
K
Q
Q
Zebra Danio
Brachydanio rerio
NP_001005206
431
47137
S358
G
T
G
T
G
G
M
S
L
R
L
G
A
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569954
506
55930
E374
S
G
G
R
K
T
P
E
L
D
Y
T
Q
S
H
Honey Bee
Apis mellifera
XP_001121386
398
44798
N330
F
F
A
K
Y
Y
E
N
F
R
V
T
N
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002327154
446
49129
Q367
I
S
A
A
V
N
L
Q
A
T
C
N
N
P
L
Maize
Zea mays
NP_001146650
428
47186
I359
R
P
E
N
D
V
P
I
P
G
N
K
T
F
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190487
438
48131
T360
D
T
M
D
G
I
V
T
V
D
P
P
P
F
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90.6
76.3
N.A.
83.3
83
N.A.
N.A.
66.9
64.1
60.8
N.A.
29.8
34.9
N.A.
N.A.
Protein Similarity:
100
N.A.
92.9
79.8
N.A.
90.9
91.1
N.A.
N.A.
78.2
78
79.8
N.A.
50
52.3
N.A.
N.A.
P-Site Identity:
100
N.A.
100
13.3
N.A.
60
60
N.A.
N.A.
0
53.3
40
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
20
N.A.
73.3
73.3
N.A.
N.A.
0
60
60
N.A.
6.6
20
N.A.
N.A.
Percent
Protein Identity:
26.6
28.7
N.A.
22.8
N.A.
N.A.
Protein Similarity:
44.6
46.3
N.A.
44
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
6.6
13.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
16
8
0
0
0
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
8
8
0
8
0
0
16
0
0
0
0
0
% D
% Glu:
31
0
16
0
0
0
8
8
0
0
0
0
8
0
0
% E
% Phe:
16
8
0
0
0
0
0
0
8
0
0
0
0
16
0
% F
% Gly:
16
8
16
16
54
54
0
8
0
8
8
47
0
0
0
% G
% His:
0
0
0
16
0
0
0
8
0
0
0
0
0
31
8
% H
% Ile:
8
0
0
0
0
8
0
16
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
8
0
0
0
8
0
0
8
8
0
8
% K
% Leu:
0
0
8
8
8
0
47
0
54
0
47
0
31
16
24
% L
% Met:
0
0
16
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
8
8
0
8
0
0
8
8
16
8
0
% N
% Pro:
0
31
0
0
0
8
16
0
8
8
8
8
16
16
8
% P
% Gln:
0
0
16
0
0
0
0
8
8
24
0
0
8
8
24
% Q
% Arg:
8
0
16
16
0
0
0
16
0
39
0
0
0
0
0
% R
% Ser:
8
8
0
8
0
0
0
8
0
0
8
8
0
8
16
% S
% Thr:
0
24
0
8
0
8
0
24
0
8
0
16
8
0
8
% T
% Val:
0
0
0
0
8
8
16
0
8
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _