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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CEP250 All Species: 10.91
Human Site: S2206 Identified Species: 21.82
UniProt: Q9BV73 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV73 NP_009117.2 2442 281137 S2206 A S V L E R D S E Q Q R L Q D
Chimpanzee Pan troglodytes XP_513109 2017 228357 K1782 Q A L S E A R K Q S S S L G E
Rhesus Macaque Macaca mulatta XP_001099508 2441 280984 S2204 A S V L E R D S E Q Q R L Q D
Dog Lupus familis XP_542975 2439 279395 L2201 A S V L E R D L E Q Q R L Q D
Cat Felis silvestris
Mouse Mus musculus Q60952 2414 276911 S2179 A S V L E R E S E Q Q R L Q E
Rat Rattus norvegicus Q9JLT0 1976 228947 E1747 Q L E E E L E E E Q S N M E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513460 1922 221583 S1700 V L Q K H L D S V R Q A L S E
Chicken Gallus gallus P10587 1979 228777 E1753 Q L E E E L D E E H S N I E T
Frog Xenopus laevis Q9PW73 1335 154049 G1118 R L A Q K L E G M D L I S K E
Zebra Danio Brachydanio rerio XP_692550 2775 330336 I2479 L T K K D Q E I R R L R I K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651216 2048 232651 E1820 S S Q R E K S E L R S K L Q T
Honey Bee Apis mellifera XP_624402 2052 240552 V1781 N E L A N N E V Q R C A L E S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.6 96.4 81.9 N.A. 78.7 21 N.A. 22.8 21.4 22.5 24 N.A. 20.7 21.6 N.A. N.A.
Protein Similarity: 100 43.6 97.9 89.9 N.A. 88.2 40.8 N.A. 43.4 41.8 37.9 47 N.A. 41.2 43 N.A. N.A.
P-Site Identity: 100 13.3 100 93.3 N.A. 86.6 20 N.A. 26.6 20 0 6.6 N.A. 26.6 6.6 N.A. N.A.
P-Site Similarity: 100 40 100 93.3 N.A. 100 40 N.A. 40 33.3 26.6 53.3 N.A. 53.3 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 9 9 9 0 9 0 0 0 0 0 17 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 42 0 0 9 0 0 0 0 25 % D
% Glu: 0 9 17 17 67 0 42 25 50 0 0 0 0 25 34 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 9 17 0 0 % I
% Lys: 0 0 9 17 9 9 0 9 0 0 0 9 0 17 0 % K
% Leu: 9 34 17 34 0 34 0 9 9 0 17 0 67 0 9 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % M
% Asn: 9 0 0 0 9 9 0 0 0 0 0 17 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 25 0 17 9 0 9 0 0 17 42 42 0 0 42 0 % Q
% Arg: 9 0 0 9 0 34 9 0 9 34 0 42 0 0 0 % R
% Ser: 9 42 0 9 0 0 9 34 0 9 34 9 9 9 9 % S
% Thr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 17 % T
% Val: 9 0 34 0 0 0 0 9 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _