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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MECR
All Species:
20.61
Human Site:
S186
Identified Species:
45.33
UniProt:
Q9BV79
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV79
NP_001019903.1
373
40428
S186
E
Q
L
Q
P
G
D
S
V
I
Q
N
A
S
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113746
373
40454
S186
E
Q
L
Q
P
G
D
S
V
I
Q
N
A
S
N
Dog
Lupus familis
XP_535334
367
39355
W179
E
Q
L
Q
P
G
D
W
V
I
Q
N
A
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCS3
373
40324
S186
E
Q
L
Q
P
G
D
S
V
I
Q
N
A
S
N
Rat
Rattus norvegicus
Q9Z311
373
40308
S186
E
Q
L
Q
P
G
D
S
V
I
Q
N
A
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6GQN8
377
41060
T188
E
E
L
K
A
G
D
T
V
I
Q
N
A
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6U9
357
39093
I168
L
C
P
G
D
T
V
I
Q
N
G
A
N
S
A
Honey Bee
Apis mellifera
XP_395130
342
38152
C168
G
Q
M
V
I
Q
L
C
K
E
W
N
Y
K
S
Nematode Worm
Caenorhab. elegans
O45903
344
38177
N168
T
V
A
Q
N
G
A
N
S
A
V
G
K
H
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LCU7
375
40805
S188
V
N
L
N
S
G
D
S
V
V
Q
N
G
A
T
Baker's Yeast
Sacchar. cerevisiae
P38071
380
42048
N176
I
D
W
N
S
N
G
N
E
W
I
I
Q
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
85.7
N.A.
82
81.7
N.A.
N.A.
N.A.
N.A.
58.8
N.A.
44.7
41.2
41.5
N.A.
Protein Similarity:
100
N.A.
98.6
90.3
N.A.
89.5
88.7
N.A.
N.A.
N.A.
N.A.
75
N.A.
61.6
59.2
57
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
6.6
13.3
13.3
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
6.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
32.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
51.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
10
0
0
10
0
10
55
19
19
% A
% Cys:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
64
0
0
0
0
0
0
0
0
% D
% Glu:
55
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
73
10
0
0
0
10
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
10
0
0
10
0
55
10
10
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
0
0
0
10
10
0
% K
% Leu:
10
0
64
0
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
19
10
10
0
19
0
10
0
73
10
10
55
% N
% Pro:
0
0
10
0
46
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
55
0
55
0
10
0
0
10
0
64
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
19
0
0
46
10
0
0
0
0
55
10
% S
% Thr:
10
0
0
0
0
10
0
10
0
0
0
0
0
0
10
% T
% Val:
10
10
0
10
0
0
10
0
64
10
10
0
0
0
10
% V
% Trp:
0
0
10
0
0
0
0
10
0
10
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _