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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MECR
All Species:
18.48
Human Site:
S192
Identified Species:
40.67
UniProt:
Q9BV79
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV79
NP_001019903.1
373
40428
S192
D
S
V
I
Q
N
A
S
N
S
G
V
G
Q
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113746
373
40454
S192
D
S
V
I
Q
N
A
S
N
S
G
V
G
Q
A
Dog
Lupus familis
XP_535334
367
39355
S185
D
W
V
I
Q
N
A
S
N
S
G
V
G
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCS3
373
40324
S192
D
S
V
I
Q
N
A
S
N
S
G
V
G
Q
A
Rat
Rattus norvegicus
Q9Z311
373
40308
S192
D
S
V
I
Q
N
A
S
N
S
G
V
G
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6GQN8
377
41060
A194
D
T
V
I
Q
N
A
A
N
S
G
V
G
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6U9
357
39093
S174
V
I
Q
N
G
A
N
S
A
V
G
Q
A
V
H
Honey Bee
Apis mellifera
XP_395130
342
38152
K174
L
C
K
E
W
N
Y
K
S
V
S
V
V
R
D
Nematode Worm
Caenorhab. elegans
O45903
344
38177
H174
A
N
S
A
V
G
K
H
V
I
Q
I
C
R
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LCU7
375
40805
A194
D
S
V
V
Q
N
G
A
T
S
I
V
G
Q
C
Baker's Yeast
Sacchar. cerevisiae
P38071
380
42048
N182
G
N
E
W
I
I
Q
N
A
G
T
S
S
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
85.7
N.A.
82
81.7
N.A.
N.A.
N.A.
N.A.
58.8
N.A.
44.7
41.2
41.5
N.A.
Protein Similarity:
100
N.A.
98.6
90.3
N.A.
89.5
88.7
N.A.
N.A.
N.A.
N.A.
75
N.A.
61.6
59.2
57
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
13.3
13.3
0
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
13.3
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
32.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
51.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
10
55
19
19
0
0
0
10
0
55
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
64
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
10
10
0
0
10
64
0
64
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
55
10
10
0
0
0
10
10
10
0
0
10
% I
% Lys:
0
0
10
0
0
0
10
10
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
10
0
73
10
10
55
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
64
0
10
0
0
0
10
10
0
64
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% R
% Ser:
0
46
10
0
0
0
0
55
10
64
10
10
10
0
10
% S
% Thr:
0
10
0
0
0
0
0
0
10
0
10
0
0
0
0
% T
% Val:
10
0
64
10
10
0
0
0
10
19
0
73
10
19
0
% V
% Trp:
0
10
0
10
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _