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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MECR
All Species:
23.94
Human Site:
T140
Identified Species:
52.67
UniProt:
Q9BV79
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV79
NP_001019903.1
373
40428
T140
A
G
L
G
T
W
R
T
E
A
V
F
S
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113746
373
40454
T140
A
G
L
G
T
W
R
T
E
A
V
F
S
E
E
Dog
Lupus familis
XP_535334
367
39355
T133
A
G
L
G
T
W
R
T
E
A
V
F
S
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCS3
373
40324
T140
A
G
L
G
T
W
R
T
E
A
V
F
S
E
E
Rat
Rattus norvegicus
Q9Z311
373
40308
T140
A
G
L
G
T
W
R
T
E
A
V
F
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6GQN8
377
41060
T142
A
G
I
G
T
W
R
T
A
A
V
L
K
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6U9
357
39093
A122
L
G
T
W
T
T
H
A
V
Y
K
E
D
Q
L
Honey Bee
Apis mellifera
XP_395130
342
38152
T122
K
V
P
K
E
I
G
T
I
E
A
S
M
L
N
Nematode Worm
Caenorhab. elegans
O45903
344
38177
N122
E
L
G
L
H
Q
E
N
D
L
F
P
I
D
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LCU7
375
40805
T142
P
S
S
G
T
W
Q
T
Y
V
V
K
E
E
S
Baker's Yeast
Sacchar. cerevisiae
P38071
380
42048
N130
A
N
Q
G
T
W
S
N
Y
R
V
F
S
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
85.7
N.A.
82
81.7
N.A.
N.A.
N.A.
N.A.
58.8
N.A.
44.7
41.2
41.5
N.A.
Protein Similarity:
100
N.A.
98.6
90.3
N.A.
89.5
88.7
N.A.
N.A.
N.A.
N.A.
75
N.A.
61.6
59.2
57
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
60
N.A.
13.3
6.6
0
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
20
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
32.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
51.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
64
0
0
0
0
0
0
10
10
55
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
10
% D
% Glu:
10
0
0
0
10
0
10
0
46
10
0
10
10
55
46
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
55
0
0
0
% F
% Gly:
0
64
10
73
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
10
0
0
0
10
0
0
% I
% Lys:
10
0
0
10
0
0
0
0
0
0
10
10
10
0
0
% K
% Leu:
10
10
46
10
0
0
0
0
0
10
0
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
0
19
0
0
0
0
0
0
19
% N
% Pro:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
10
0
0
10
10
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
55
0
0
10
0
0
0
0
0
% R
% Ser:
0
10
10
0
0
0
10
0
0
0
0
10
55
10
19
% S
% Thr:
0
0
10
0
82
10
0
73
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
10
10
73
0
0
0
0
% V
% Trp:
0
0
0
10
0
73
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
19
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _