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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MECR
All Species:
17.88
Human Site:
Y353
Identified Species:
39.33
UniProt:
Q9BV79
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV79
NP_001019903.1
373
40428
Y353
S
Q
V
P
L
Q
D
Y
Q
S
A
L
E
A
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113746
373
40454
Y353
S
Q
V
P
L
Q
D
Y
Q
S
A
L
E
A
S
Dog
Lupus familis
XP_535334
367
39355
Y346
S
E
V
P
L
Q
D
Y
E
R
A
L
E
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCS3
373
40324
Y353
S
E
V
P
L
Q
G
Y
Q
Q
A
L
E
A
S
Rat
Rattus norvegicus
Q9Z311
373
40308
Y353
S
G
I
P
L
Q
D
Y
Q
Q
A
L
E
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6GQN8
377
41060
Q355
I
C
T
Q
V
Q
L
Q
D
F
R
K
A
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6U9
357
39093
K332
H
E
M
V
P
L
A
K
F
K
D
A
A
A
A
Honey Bee
Apis mellifera
XP_395130
342
38152
V321
F
H
Q
Y
Q
E
A
V
I
N
A
L
H
T
D
Nematode Worm
Caenorhab. elegans
O45903
344
38177
D323
I
V
K
N
R
L
E
D
H
A
K
A
L
D
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LCU7
375
40805
P355
L
V
P
F
E
E
F
P
V
A
L
D
K
A
L
Baker's Yeast
Sacchar. cerevisiae
P38071
380
42048
T351
I
E
T
L
T
W
N
T
N
T
T
T
D
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
85.7
N.A.
82
81.7
N.A.
N.A.
N.A.
N.A.
58.8
N.A.
44.7
41.2
41.5
N.A.
Protein Similarity:
100
N.A.
98.6
90.3
N.A.
89.5
88.7
N.A.
N.A.
N.A.
N.A.
75
N.A.
61.6
59.2
57
N.A.
P-Site Identity:
100
N.A.
100
80
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
6.6
13.3
0
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
26.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
32.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
51.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
19
0
0
19
55
19
19
64
10
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
37
10
10
0
10
10
10
10
10
% D
% Glu:
0
37
0
0
10
19
10
0
10
0
0
0
46
10
10
% E
% Phe:
10
0
0
10
0
0
10
0
10
10
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
10
10
0
0
0
0
0
0
10
0
0
0
10
0
0
% H
% Ile:
28
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
10
0
10
10
10
10
0
0
% K
% Leu:
10
0
0
10
46
19
10
0
0
0
10
55
10
10
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
10
10
0
0
0
0
0
% N
% Pro:
0
0
10
46
10
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
19
10
10
10
55
0
10
37
19
0
0
0
0
10
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
10
0
0
0
0
% R
% Ser:
46
0
0
0
0
0
0
0
0
19
0
0
0
0
46
% S
% Thr:
0
0
19
0
10
0
0
10
0
10
10
10
0
10
10
% T
% Val:
0
19
37
10
10
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _