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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL11A All Species: 6.67
Human Site: S156 Identified Species: 10.48
UniProt: Q9BV86 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV86 NP_054783.2 223 25387 S156 F L R R C K G S L R P N G I I
Chimpanzee Pan troglodytes XP_520309 223 25269 S156 F L G R C K G S L R P N G I I
Rhesus Macaque Macaca mulatta XP_001093866 283 32445 G211 F L S R C R D G L K E N G V I
Dog Lupus familis XP_548421 245 27205 G178 F L R R C K Q G L R P N G I I
Cat Felis silvestris
Mouse Mus musculus Q8R2U4 223 25402 G156 F L R R C K R G L R P N G I I
Rat Rattus norvegicus Q5BJX0 223 25446 G156 F L R R C R R G L R P N G I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514588 353 38867 G267 F L S R C R A G L K E N G V V
Chicken Gallus gallus XP_423291 138 15770 L81 R I T K R L L L P L F K T V D
Frog Xenopus laevis NP_001090080 224 25381 G157 F L Q R C R L G L R P N G I I
Zebra Danio Brachydanio rerio NP_998063 223 25246 G156 F L R R C R S G L R P E G L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623109 237 27478 G164 F L K K C S C G L R S N G I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784765 226 25700 G159 F L K R A R T G L T E T G M I
Poplar Tree Populus trichocarpa XP_002317082 276 31081 G186 F F N R A K I G L K P G G F F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199258 334 37725 Y244 F F N R A K G Y L K P G G F F
Baker's Yeast Sacchar. cerevisiae P38340 232 26049 G160 F L K R C I V G L Q P N G T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 40.9 84 N.A. 94.1 94.1 N.A. 30 51.5 73.6 71.7 N.A. N.A. 45.9 N.A. 50.4
Protein Similarity: 100 99.5 57.2 88.1 N.A. 97.3 97.3 N.A. 43.3 58.7 89.7 85.1 N.A. N.A. 58.6 N.A. 68.5
P-Site Identity: 100 93.3 53.3 86.6 N.A. 86.6 80 N.A. 46.6 0 73.3 66.6 N.A. N.A. 60 N.A. 40
P-Site Similarity: 100 93.3 73.3 86.6 N.A. 86.6 86.6 N.A. 73.3 20 86.6 80 N.A. N.A. 73.3 N.A. 60
Percent
Protein Identity: 35.1 N.A. N.A. 29.9 37.5 N.A.
Protein Similarity: 48.9 N.A. N.A. 41.6 55.1 N.A.
P-Site Identity: 40 N.A. N.A. 46.6 60 N.A.
P-Site Similarity: 46.6 N.A. N.A. 53.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 20 0 7 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 74 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 20 7 0 0 0 % E
% Phe: 94 14 0 0 0 0 0 0 0 0 7 0 0 14 14 % F
% Gly: 0 0 7 0 0 0 20 74 0 0 0 14 94 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 7 7 0 0 0 0 0 0 47 74 % I
% Lys: 0 0 20 14 0 40 0 0 0 27 0 7 0 0 0 % K
% Leu: 0 80 0 0 0 7 14 7 94 7 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 14 0 0 0 0 0 0 0 0 67 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 67 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 7 0 0 7 0 0 0 0 0 % Q
% Arg: 7 0 34 87 7 40 14 0 0 54 0 0 0 0 0 % R
% Ser: 0 0 14 0 0 7 7 14 0 0 7 0 0 0 0 % S
% Thr: 0 0 7 0 0 0 7 0 0 7 0 7 7 7 0 % T
% Val: 0 0 0 0 0 0 7 0 0 0 0 0 0 20 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _