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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL11A
All Species:
16.06
Human Site:
S39
Identified Species:
25.24
UniProt:
Q9BV86
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV86
NP_054783.2
223
25387
S39
G
G
Y
G
H
I
S
S
I
D
I
N
S
S
R
Chimpanzee
Pan troglodytes
XP_520309
223
25269
S39
G
G
Y
G
H
I
S
S
I
D
I
N
S
S
R
Rhesus Macaque
Macaca mulatta
XP_001093866
283
32445
S95
G
N
F
I
E
L
S
S
P
D
I
Q
A
S
R
Dog
Lupus familis
XP_548421
245
27205
S61
G
G
Y
G
H
I
S
S
I
D
I
S
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2U4
223
25402
N39
G
G
Y
G
H
I
S
N
I
D
L
N
S
S
R
Rat
Rattus norvegicus
Q5BJX0
223
25446
N39
G
G
Y
G
H
I
S
N
I
D
L
N
S
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514588
353
38867
A150
V
P
F
K
S
W
A
A
T
G
S
E
Y
G
G
Chicken
Gallus gallus
XP_423291
138
15770
Frog
Xenopus laevis
NP_001090080
224
25381
N39
G
G
Y
G
H
I
S
N
V
D
L
N
G
S
K
Zebra Danio
Brachydanio rerio
NP_998063
223
25246
S39
G
G
Y
G
S
I
S
S
I
D
I
N
G
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623109
237
27478
Q48
G
G
F
G
F
I
S
Q
I
D
I
K
G
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784765
226
25700
G41
G
G
F
G
Q
I
S
G
E
D
I
N
G
S
L
Poplar Tree
Populus trichocarpa
XP_002317082
276
31081
D60
G
G
Y
G
H
V
N
D
A
D
V
K
G
S
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_199258
334
37725
D120
G
G
Y
G
H
V
N
D
A
D
I
I
G
S
E
Baker's Yeast
Sacchar. cerevisiae
P38340
232
26049
M41
E
G
T
V
V
P
T
M
D
V
L
G
S
N
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
40.9
84
N.A.
94.1
94.1
N.A.
30
51.5
73.6
71.7
N.A.
N.A.
45.9
N.A.
50.4
Protein Similarity:
100
99.5
57.2
88.1
N.A.
97.3
97.3
N.A.
43.3
58.7
89.7
85.1
N.A.
N.A.
58.6
N.A.
68.5
P-Site Identity:
100
100
46.6
93.3
N.A.
86.6
86.6
N.A.
0
0
66.6
80
N.A.
N.A.
60
N.A.
60
P-Site Similarity:
100
100
66.6
100
N.A.
100
100
N.A.
20
0
93.3
86.6
N.A.
N.A.
66.6
N.A.
66.6
Percent
Protein Identity:
35.1
N.A.
N.A.
29.9
37.5
N.A.
Protein Similarity:
48.9
N.A.
N.A.
41.6
55.1
N.A.
P-Site Identity:
46.6
N.A.
N.A.
53.3
13.3
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
66.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
7
14
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
14
7
80
0
0
0
0
0
% D
% Glu:
7
0
0
0
7
0
0
0
7
0
0
7
0
0
14
% E
% Phe:
0
0
27
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
80
80
0
74
0
0
0
7
0
7
0
7
40
7
7
% G
% His:
0
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
60
0
0
47
0
54
7
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
0
14
0
0
14
% K
% Leu:
0
0
0
0
0
7
0
0
0
0
27
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
14
20
0
0
0
47
0
7
7
% N
% Pro:
0
7
0
0
0
7
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
7
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% R
% Ser:
0
0
0
0
14
0
67
34
0
0
7
7
40
80
0
% S
% Thr:
0
0
7
0
0
0
7
0
7
0
0
0
0
0
7
% T
% Val:
7
0
0
7
7
14
0
0
7
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
60
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _