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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL11A All Species: 20.61
Human Site: S44 Identified Species: 32.38
UniProt: Q9BV86 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV86 NP_054783.2 223 25387 S44 I S S I D I N S S R K F L Q R
Chimpanzee Pan troglodytes XP_520309 223 25269 S44 I S S I D I N S S R K F L Q R
Rhesus Macaque Macaca mulatta XP_001093866 283 32445 A100 L S S P D I Q A S R K F L R K
Dog Lupus familis XP_548421 245 27205 S66 I S S I D I S S S R K F L Q R
Cat Felis silvestris
Mouse Mus musculus Q8R2U4 223 25402 S44 I S N I D L N S S R K F L Q R
Rat Rattus norvegicus Q5BJX0 223 25446 S44 I S N I D L N S S R K F L Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514588 353 38867 Y155 W A A T G S E Y G G Q R Q G V
Chicken Gallus gallus XP_423291 138 15770
Frog Xenopus laevis NP_001090080 224 25381 G44 I S N V D L N G S K K F L Q R
Zebra Danio Brachydanio rerio NP_998063 223 25246 G44 I S S I D I N G S K K F L Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623109 237 27478 G53 I S Q I D I K G S T K F L K A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784765 226 25700 G46 I S G E D I N G S L E F L K P
Poplar Tree Populus trichocarpa XP_002317082 276 31081 G65 V N D A D V K G S E G F L Q T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199258 334 37725 G125 V N D A D I I G S E V F L K T
Baker's Yeast Sacchar. cerevisiae P38340 232 26049 S46 P T M D V L G S N N F L R K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 40.9 84 N.A. 94.1 94.1 N.A. 30 51.5 73.6 71.7 N.A. N.A. 45.9 N.A. 50.4
Protein Similarity: 100 99.5 57.2 88.1 N.A. 97.3 97.3 N.A. 43.3 58.7 89.7 85.1 N.A. N.A. 58.6 N.A. 68.5
P-Site Identity: 100 100 60 93.3 N.A. 86.6 86.6 N.A. 0 0 66.6 80 N.A. N.A. 60 N.A. 53.3
P-Site Similarity: 100 100 86.6 100 N.A. 100 100 N.A. 20 0 93.3 93.3 N.A. N.A. 66.6 N.A. 66.6
Percent
Protein Identity: 35.1 N.A. N.A. 29.9 37.5 N.A.
Protein Similarity: 48.9 N.A. N.A. 41.6 55.1 N.A.
P-Site Identity: 33.3 N.A. N.A. 33.3 6.6 N.A.
P-Site Similarity: 53.3 N.A. N.A. 53.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 14 0 0 0 7 0 0 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 14 7 80 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 0 0 7 0 0 14 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 80 0 0 0 % F
% Gly: 0 0 7 0 7 0 7 40 7 7 7 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 60 0 0 47 0 54 7 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 14 0 0 14 60 0 0 27 14 % K
% Leu: 7 0 0 0 0 27 0 0 0 7 0 7 80 0 7 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 14 20 0 0 0 47 0 7 7 0 0 0 0 0 % N
% Pro: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % P
% Gln: 0 0 7 0 0 0 7 0 0 0 7 0 7 54 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 40 0 7 7 7 40 % R
% Ser: 0 67 34 0 0 7 7 40 80 0 0 0 0 0 0 % S
% Thr: 0 7 0 7 0 0 0 0 0 7 0 0 0 0 14 % T
% Val: 14 0 0 7 7 7 0 0 0 0 7 0 0 0 7 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _