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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL11A All Species: 18.79
Human Site: S63 Identified Species: 29.52
UniProt: Q9BV86 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV86 NP_054783.2 223 25387 S63 G P N K T G T S C A L D C G A
Chimpanzee Pan troglodytes XP_520309 223 25269 S63 G P N K T G T S C A L D C G A
Rhesus Macaque Macaca mulatta XP_001093866 283 32445 C119 P G R A G T D C A L D C G S G
Dog Lupus familis XP_548421 245 27205 S85 G P N K T G T S C A L D C G A
Cat Felis silvestris
Mouse Mus musculus Q8R2U4 223 25402 S63 G P N K T G T S C A L D C G A
Rat Rattus norvegicus Q5BJX0 223 25446 S63 G P N K T G T S C A L D C G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514588 353 38867 D174 G P G K T G T D C A L D C G S
Chicken Gallus gallus XP_423291 138 15770
Frog Xenopus laevis NP_001090080 224 25381 N63 E G S N K T G N A C A L D C G
Zebra Danio Brachydanio rerio NP_998063 223 25246 G63 G Q G K T G T G C A L D C G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623109 237 27478 F72 E N P P S K T F A L D C G A G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784765 226 25700 S65 A W A E R V G S N R A L D C G
Poplar Tree Populus trichocarpa XP_002317082 276 31081 D84 L F V D G G I D R H L V A L D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199258 334 37725 A144 R L V N N V G A N Q H L V A L
Baker's Yeast Sacchar. cerevisiae P38340 232 26049 K65 L P Q E N N V K Y A V D I G A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 40.9 84 N.A. 94.1 94.1 N.A. 30 51.5 73.6 71.7 N.A. N.A. 45.9 N.A. 50.4
Protein Similarity: 100 99.5 57.2 88.1 N.A. 97.3 97.3 N.A. 43.3 58.7 89.7 85.1 N.A. N.A. 58.6 N.A. 68.5
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 80 0 0 80 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 86.6 0 13.3 80 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: 35.1 N.A. N.A. 29.9 37.5 N.A.
Protein Similarity: 48.9 N.A. N.A. 41.6 55.1 N.A.
P-Site Identity: 13.3 N.A. N.A. 0 33.3 N.A.
P-Site Similarity: 13.3 N.A. N.A. 6.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 7 0 0 0 7 20 54 14 0 7 14 47 % A
% Cys: 0 0 0 0 0 0 0 7 47 7 0 14 47 14 0 % C
% Asp: 0 0 0 7 0 0 7 14 0 0 14 54 14 0 7 % D
% Glu: 14 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 47 14 14 0 14 54 20 7 0 0 0 0 14 54 27 % G
% His: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 47 7 7 0 7 0 0 0 0 0 0 0 % K
% Leu: 14 7 0 0 0 0 0 0 0 14 54 20 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 34 14 14 7 0 7 14 0 0 0 0 0 0 % N
% Pro: 7 47 7 7 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 7 0 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 7 0 7 0 7 0 0 0 7 7 0 0 0 0 0 % R
% Ser: 0 0 7 0 7 0 0 40 0 0 0 0 0 7 7 % S
% Thr: 0 0 0 0 47 14 54 0 0 0 0 0 0 0 0 % T
% Val: 0 0 14 0 0 14 7 0 0 0 7 7 7 0 0 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _