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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL11A All Species: 24.85
Human Site: T2 Identified Species: 39.05
UniProt: Q9BV86 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV86 NP_054783.2 223 25387 T2 _ _ _ _ _ _ M T S E V I E D E
Chimpanzee Pan troglodytes XP_520309 223 25269 T2 _ _ _ _ _ _ M T S E V I E D E
Rhesus Macaque Macaca mulatta XP_001093866 283 32445 T58 L V K L Y A L T S Q V I N G E
Dog Lupus familis XP_548421 245 27205 T24 D S V G D S M T S E V I E D E
Cat Felis silvestris
Mouse Mus musculus Q8R2U4 223 25402 T2 _ _ _ _ _ _ M T S E V I E D E
Rat Rattus norvegicus Q5BJX0 223 25446 T2 _ _ _ _ _ _ M T S E V I E D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514588 353 38867 T113 S Y N T D I T T T N Y N N V S
Chicken Gallus gallus XP_423291 138 15770
Frog Xenopus laevis NP_001090080 224 25381 S2 _ _ _ _ _ _ M S T E L V E D E
Zebra Danio Brachydanio rerio NP_998063 223 25246 E2 _ _ _ _ _ _ M E D C L I E D Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623109 237 27478 K11 L S S S K M E K E E N T L E E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784765 226 25700 P4 _ _ _ _ M E R P A V D Q M T K
Poplar Tree Populus trichocarpa XP_002317082 276 31081 H23 P D E M W L E H T G D T N K K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199258 334 37725 G83 E M W R E E I G E G D E T K K
Baker's Yeast Sacchar. cerevisiae P38340 232 26049 P4 _ _ _ _ M D V P A D S H I K Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 40.9 84 N.A. 94.1 94.1 N.A. 30 51.5 73.6 71.7 N.A. N.A. 45.9 N.A. 50.4
Protein Similarity: 100 99.5 57.2 88.1 N.A. 97.3 97.3 N.A. 43.3 58.7 89.7 85.1 N.A. N.A. 58.6 N.A. 68.5
P-Site Identity: 100 100 33.3 60 N.A. 100 100 N.A. 6.6 0 55.5 44.4 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 100 53.3 66.6 N.A. 100 100 N.A. 26.6 0 100 66.6 N.A. N.A. 20 N.A. 18.1
Percent
Protein Identity: 35.1 N.A. N.A. 29.9 37.5 N.A.
Protein Similarity: 48.9 N.A. N.A. 41.6 55.1 N.A.
P-Site Identity: 0 N.A. N.A. 0 0 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 27.2 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 14 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 7 7 0 0 14 7 0 0 7 7 20 0 0 47 0 % D
% Glu: 7 0 7 0 7 14 14 7 14 47 0 7 47 7 54 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 7 0 14 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 7 7 0 0 0 0 47 7 0 0 % I
% Lys: 0 0 7 0 7 0 0 7 0 0 0 0 0 20 20 % K
% Leu: 14 0 0 7 0 7 7 0 0 0 14 0 7 0 0 % L
% Met: 0 7 0 7 14 7 47 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 7 7 7 20 0 0 % N
% Pro: 7 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 7 % Q
% Arg: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % R
% Ser: 7 14 7 7 0 7 0 7 40 0 7 0 0 0 7 % S
% Thr: 0 0 0 7 0 0 7 47 20 0 0 14 7 7 0 % T
% Val: 0 7 7 0 0 0 7 0 0 7 40 7 0 7 0 % V
% Trp: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 0 0 0 0 7 0 0 0 7 % Y
% Spaces: 54 54 54 54 40 40 0 0 0 0 0 0 0 0 0 % _