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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL11A All Species: 26.06
Human Site: T62 Identified Species: 40.95
UniProt: Q9BV86 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV86 NP_054783.2 223 25387 T62 E G P N K T G T S C A L D C G
Chimpanzee Pan troglodytes XP_520309 223 25269 T62 E G P N K T G T S C A L D C G
Rhesus Macaque Macaca mulatta XP_001093866 283 32445 D118 G P G R A G T D C A L D C G S
Dog Lupus familis XP_548421 245 27205 T84 E G P N K T G T S C A L D C G
Cat Felis silvestris
Mouse Mus musculus Q8R2U4 223 25402 T62 E G P N K T G T S C A L D C G
Rat Rattus norvegicus Q5BJX0 223 25446 T62 E G P N K T G T S C A L D C G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514588 353 38867 T173 S G P G K T G T D C A L D C G
Chicken Gallus gallus XP_423291 138 15770
Frog Xenopus laevis NP_001090080 224 25381 G62 Q E G S N K T G N A C A L D C
Zebra Danio Brachydanio rerio NP_998063 223 25246 T62 E G Q G K T G T G C A L D C G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623109 237 27478 T71 L E N P P S K T F A L D C G A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784765 226 25700 G64 C A W A E R V G S N R A L D C
Poplar Tree Populus trichocarpa XP_002317082 276 31081 I83 E L F V D G G I D R H L V A L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199258 334 37725 G143 E R L V N N V G A N Q H L V A
Baker's Yeast Sacchar. cerevisiae P38340 232 26049 V64 M L P Q E N N V K Y A V D I G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 40.9 84 N.A. 94.1 94.1 N.A. 30 51.5 73.6 71.7 N.A. N.A. 45.9 N.A. 50.4
Protein Similarity: 100 99.5 57.2 88.1 N.A. 97.3 97.3 N.A. 43.3 58.7 89.7 85.1 N.A. N.A. 58.6 N.A. 68.5
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 80 0 0 80 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 80 0 20 80 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: 35.1 N.A. N.A. 29.9 37.5 N.A.
Protein Similarity: 48.9 N.A. N.A. 41.6 55.1 N.A.
P-Site Identity: 20 N.A. N.A. 6.6 26.6 N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 7 0 0 0 7 20 54 14 0 7 14 % A
% Cys: 7 0 0 0 0 0 0 0 7 47 7 0 14 47 14 % C
% Asp: 0 0 0 0 7 0 0 7 14 0 0 14 54 14 0 % D
% Glu: 54 14 0 0 14 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 7 47 14 14 0 14 54 20 7 0 0 0 0 14 54 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 0 0 0 7 0 % I
% Lys: 0 0 0 0 47 7 7 0 7 0 0 0 0 0 0 % K
% Leu: 7 14 7 0 0 0 0 0 0 0 14 54 20 0 7 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 34 14 14 7 0 7 14 0 0 0 0 0 % N
% Pro: 0 7 47 7 7 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 7 7 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 7 0 7 0 7 0 0 0 7 7 0 0 0 0 % R
% Ser: 7 0 0 7 0 7 0 0 40 0 0 0 0 0 7 % S
% Thr: 0 0 0 0 0 47 14 54 0 0 0 0 0 0 0 % T
% Val: 0 0 0 14 0 0 14 7 0 0 0 7 7 7 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _