Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL11A All Species: 48.79
Human Site: Y129 Identified Species: 76.67
UniProt: Q9BV86 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV86 NP_054783.2 223 25387 Y129 F T P E P D S Y D V I W I Q W
Chimpanzee Pan troglodytes XP_520309 223 25269 Y129 F T P E P D S Y D V I W I Q W
Rhesus Macaque Macaca mulatta XP_001093866 283 32445 Y184 F T P P F R R Y D V I W I Q W
Dog Lupus familis XP_548421 245 27205 Y151 F S P E P N S Y D V I W I Q W
Cat Felis silvestris
Mouse Mus musculus Q8R2U4 223 25402 Y129 F S P E P G S Y D V I W I Q W
Rat Rattus norvegicus Q5BJX0 223 25446 Y129 F S P E P S S Y D V I W I Q W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514588 353 38867 Y240 F T P A N G R Y D V I W I Q W
Chicken Gallus gallus XP_423291 138 15770 R54 K F L Q R F L R D G P N R T G
Frog Xenopus laevis NP_001090080 224 25381 Y130 F S P E P N R Y D V I W I Q W
Zebra Danio Brachydanio rerio NP_998063 223 25246 Y129 F Q P Q P E R Y D V I W I Q W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623109 237 27478 Y137 F Y F N T K K Y D V I W C Q W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784765 226 25700 Y132 F T P Q P E H Y D V I W C Q W
Poplar Tree Populus trichocarpa XP_002317082 276 31081 Y159 F T P D A G R Y D V I W V Q W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199258 334 37725 Y217 F T P A A G R Y D V I W V Q W
Baker's Yeast Sacchar. cerevisiae P38340 232 26049 Y133 W T P D A G K Y W L I W C Q W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 40.9 84 N.A. 94.1 94.1 N.A. 30 51.5 73.6 71.7 N.A. N.A. 45.9 N.A. 50.4
Protein Similarity: 100 99.5 57.2 88.1 N.A. 97.3 97.3 N.A. 43.3 58.7 89.7 85.1 N.A. N.A. 58.6 N.A. 68.5
P-Site Identity: 100 100 73.3 86.6 N.A. 86.6 86.6 N.A. 73.3 6.6 80 73.3 N.A. N.A. 53.3 N.A. 73.3
P-Site Similarity: 100 100 73.3 100 N.A. 93.3 93.3 N.A. 73.3 13.3 93.3 86.6 N.A. N.A. 53.3 N.A. 86.6
Percent
Protein Identity: 35.1 N.A. N.A. 29.9 37.5 N.A.
Protein Similarity: 48.9 N.A. N.A. 41.6 55.1 N.A.
P-Site Identity: 66.6 N.A. N.A. 66.6 46.6 N.A.
P-Site Similarity: 80 N.A. N.A. 73.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 20 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % C
% Asp: 0 0 0 14 0 14 0 0 94 0 0 0 0 0 0 % D
% Glu: 0 0 0 40 0 14 0 0 0 0 0 0 0 0 0 % E
% Phe: 87 7 7 0 7 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 34 0 0 0 7 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 94 0 60 0 0 % I
% Lys: 7 0 0 0 0 7 14 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 7 0 0 0 7 0 0 7 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 14 0 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 87 7 54 0 0 0 0 0 7 0 0 0 0 % P
% Gln: 0 7 0 20 0 0 0 0 0 0 0 0 0 94 0 % Q
% Arg: 0 0 0 0 7 7 40 7 0 0 0 0 7 0 0 % R
% Ser: 0 27 0 0 0 7 34 0 0 0 0 0 0 0 0 % S
% Thr: 0 54 0 0 7 0 0 0 0 0 0 0 0 7 0 % T
% Val: 0 0 0 0 0 0 0 0 0 87 0 0 14 0 0 % V
% Trp: 7 0 0 0 0 0 0 0 7 0 0 94 0 0 94 % W
% Tyr: 0 7 0 0 0 0 0 94 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _