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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL11A All Species: 38.18
Human Site: Y13 Identified Species: 60
UniProt: Q9BV86 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV86 NP_054783.2 223 25387 Y13 I E D E K Q F Y S K A K T Y W
Chimpanzee Pan troglodytes XP_520309 223 25269 Y13 I E D E K Q F Y S K A K T Y W
Rhesus Macaque Macaca mulatta XP_001093866 283 32445 Y69 I N G E M Q F Y A R A K L F Y
Dog Lupus familis XP_548421 245 27205 Y35 I E D E K Q F Y S K A K T Y W
Cat Felis silvestris
Mouse Mus musculus Q8R2U4 223 25402 Y13 I E D E K Q F Y S K A K T Y W
Rat Rattus norvegicus Q5BJX0 223 25446 Y13 I E D E K Q F Y S K A K T Y W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514588 353 38867 R124 N N V S P Q K R D E V P R F I
Chicken Gallus gallus XP_423291 138 15770
Frog Xenopus laevis NP_001090080 224 25381 Y13 V E D E T Q F Y G K A Q N Y W
Zebra Danio Brachydanio rerio NP_998063 223 25246 Y13 I E D Q T S F Y S E A E H Y W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623109 237 27478 Y22 T L E E H E F Y T A A A K Y W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784765 226 25700 Y15 Q M T K E S F Y N D A K D Y W
Poplar Tree Populus trichocarpa XP_002317082 276 31081 Y34 T N K K T Q W Y R D G V A Y W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199258 334 37725 Y94 E T K K T Q W Y R D G V S Y W
Baker's Yeast Sacchar. cerevisiae P38340 232 26049 I15 H I K Y E D A I D Y W T D V D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 40.9 84 N.A. 94.1 94.1 N.A. 30 51.5 73.6 71.7 N.A. N.A. 45.9 N.A. 50.4
Protein Similarity: 100 99.5 57.2 88.1 N.A. 97.3 97.3 N.A. 43.3 58.7 89.7 85.1 N.A. N.A. 58.6 N.A. 68.5
P-Site Identity: 100 100 46.6 100 N.A. 100 100 N.A. 6.6 0 66.6 60 N.A. N.A. 40 N.A. 40
P-Site Similarity: 100 100 73.3 100 N.A. 100 100 N.A. 20 0 80 80 N.A. N.A. 60 N.A. 60
Percent
Protein Identity: 35.1 N.A. N.A. 29.9 37.5 N.A.
Protein Similarity: 48.9 N.A. N.A. 41.6 55.1 N.A.
P-Site Identity: 26.6 N.A. N.A. 26.6 0 N.A.
P-Site Similarity: 40 N.A. N.A. 46.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 0 7 7 67 7 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 47 0 0 7 0 0 14 20 0 0 14 0 7 % D
% Glu: 7 47 7 54 14 7 0 0 0 14 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 67 0 0 0 0 0 0 14 0 % F
% Gly: 0 0 7 0 0 0 0 0 7 0 14 0 0 0 0 % G
% His: 7 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 47 7 0 0 0 0 0 7 0 0 0 0 0 0 7 % I
% Lys: 0 0 20 20 34 0 7 0 0 40 0 47 7 0 0 % K
% Leu: 0 7 0 0 0 0 0 0 0 0 0 0 7 0 0 % L
% Met: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 20 0 0 0 0 0 0 7 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 7 0 0 7 0 67 0 0 0 0 0 7 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 7 14 7 0 0 7 0 0 % R
% Ser: 0 0 0 7 0 14 0 0 40 0 0 0 7 0 0 % S
% Thr: 14 7 7 0 27 0 0 0 7 0 0 7 34 0 0 % T
% Val: 7 0 7 0 0 0 0 0 0 0 7 14 0 7 0 % V
% Trp: 0 0 0 0 0 0 14 0 0 0 7 0 0 0 74 % W
% Tyr: 0 0 0 7 0 0 0 80 0 7 0 0 0 74 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _