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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL11A All Species: 30.91
Human Site: Y215 Identified Species: 48.57
UniProt: Q9BV86 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV86 NP_054783.2 223 25387 Y215 E N L P D E I Y H V Y S F A L
Chimpanzee Pan troglodytes XP_520309 223 25269 Y215 E N L P D E I Y H V Y S F A L
Rhesus Macaque Macaca mulatta XP_001093866 283 32445 I270 E G F P E Q C I P V W M F T L
Dog Lupus familis XP_548421 245 27205 Y237 E N L P D E I Y H V Y S L A L
Cat Felis silvestris
Mouse Mus musculus Q8R2U4 223 25402 Y215 E N L P D E I Y H V Y S F A L
Rat Rattus norvegicus Q5BJX0 223 25446 Y215 E N L P D E I Y H V Y S F A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514588 353 38867 V326 E G F P D Q C V P V W M L A L
Chicken Gallus gallus XP_423291 138 15770 V131 P E P N S Y D V I W I Q W V I
Frog Xenopus laevis NP_001090080 224 25381 Y216 E N F P D E I Y H V F S F A M
Zebra Danio Brachydanio rerio NP_998063 223 25246 Y215 Q N F P E E I Y Q V H A L A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623109 237 27478 Y224 H K F P R G L Y P V Y M F A L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784765 226 25700 F218 K R F P L G L F T V R M Y A L
Poplar Tree Populus trichocarpa XP_002317082 276 31081 F245 K G L P K E L F A V K M Y A L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199258 334 37725 F303 K G L P Q E L F A V K M Y A L
Baker's Yeast Sacchar. cerevisiae P38340 232 26049 Y220 R G L P R E L Y P V R M Y A L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 40.9 84 N.A. 94.1 94.1 N.A. 30 51.5 73.6 71.7 N.A. N.A. 45.9 N.A. 50.4
Protein Similarity: 100 99.5 57.2 88.1 N.A. 97.3 97.3 N.A. 43.3 58.7 89.7 85.1 N.A. N.A. 58.6 N.A. 68.5
P-Site Identity: 100 100 33.3 93.3 N.A. 100 100 N.A. 40 0 80 53.3 N.A. N.A. 46.6 N.A. 26.6
P-Site Similarity: 100 100 53.3 93.3 N.A. 100 100 N.A. 53.3 13.3 93.3 80 N.A. N.A. 53.3 N.A. 53.3
Percent
Protein Identity: 35.1 N.A. N.A. 29.9 37.5 N.A.
Protein Similarity: 48.9 N.A. N.A. 41.6 55.1 N.A.
P-Site Identity: 40 N.A. N.A. 40 46.6 N.A.
P-Site Similarity: 66.6 N.A. N.A. 66.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 14 0 0 7 0 87 0 % A
% Cys: 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 47 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 54 7 0 0 14 67 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 40 0 0 0 0 20 0 0 7 0 47 0 0 % F
% Gly: 0 34 0 0 0 14 0 0 0 0 0 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 40 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 47 7 7 0 7 0 0 0 7 % I
% Lys: 20 7 0 0 7 0 0 0 0 0 14 0 0 0 0 % K
% Leu: 0 0 54 0 7 0 34 0 0 0 0 0 20 0 87 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 47 0 0 7 % M
% Asn: 0 47 0 7 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 7 94 0 0 0 0 27 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 7 14 0 0 7 0 0 7 0 0 0 % Q
% Arg: 7 7 0 0 14 0 0 0 0 0 14 0 0 0 0 % R
% Ser: 0 0 0 0 7 0 0 0 0 0 0 40 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % T
% Val: 0 0 0 0 0 0 0 14 0 94 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 14 0 7 0 0 % W
% Tyr: 0 0 0 0 0 7 0 60 0 0 40 0 27 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _