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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM2
All Species:
19.7
Human Site:
S557
Identified Species:
48.15
UniProt:
Q9BV94
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV94
NP_001138497.1
578
64753
S557
K
Q
K
V
P
L
L
S
C
P
S
Q
P
F
T
Chimpanzee
Pan troglodytes
XP_514601
578
64734
S557
K
Q
K
V
P
L
L
S
C
P
S
Q
P
F
T
Rhesus Macaque
Macaca mulatta
XP_001101476
578
64836
S557
K
Q
K
V
P
L
L
S
C
P
S
Q
P
F
T
Dog
Lupus familis
XP_534400
577
64681
S556
K
Q
K
V
P
L
L
S
C
P
S
Q
P
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q925U4
652
73682
R632
N
R
V
P
D
E
R
R
Y
S
L
P
L
K
S
Rat
Rattus norvegicus
NP_001004230
576
64421
S555
R
Q
R
A
P
L
L
S
C
P
S
Q
P
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GQB9
913
102717
L807
Q
K
Q
A
L
E
D
L
F
M
T
P
E
E
I
Zebra Danio
Brachydanio rerio
XP_696207
423
47287
C403
R
K
A
P
V
L
S
C
P
T
Q
P
F
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122669
600
67917
E568
P
A
M
I
N
N
N
E
S
F
I
K
Q
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
T760
K
K
H
S
P
V
L
T
S
N
G
T
R
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
96.1
N.A.
37.7
94.1
N.A.
N.A.
N.A.
26
54.6
N.A.
N.A.
53
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
98
N.A.
53.9
97.5
N.A.
N.A.
N.A.
37.9
65.7
N.A.
N.A.
68.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
80
N.A.
N.A.
N.A.
0
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
13.3
93.3
N.A.
N.A.
N.A.
26.6
20
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
20
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
50
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
20
0
10
0
0
0
0
10
20
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
10
50
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
10
% I
% Lys:
50
30
40
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
0
0
10
60
60
10
0
0
10
0
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
10
10
0
0
10
0
0
0
10
10
% N
% Pro:
10
0
0
20
60
0
0
0
10
50
0
30
50
0
0
% P
% Gln:
10
50
10
0
0
0
0
0
0
0
10
50
10
0
0
% Q
% Arg:
20
10
10
0
0
0
10
10
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
10
0
0
10
50
20
10
50
0
0
10
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
10
10
10
0
0
50
% T
% Val:
0
0
10
40
10
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _