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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EDEM2 All Species: 28.18
Human Site: T384 Identified Species: 68.89
UniProt: Q9BV94 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV94 NP_001138497.1 578 64753 T384 A M Y L Y R A T G D P T L L E
Chimpanzee Pan troglodytes XP_514601 578 64734 T384 A M Y L Y R A T G D P T L L E
Rhesus Macaque Macaca mulatta XP_001101476 578 64836 T384 A M Y L Y R A T G D P T L L E
Dog Lupus familis XP_534400 577 64681 T384 A M Y L Y R A T G D P T L L E
Cat Felis silvestris
Mouse Mus musculus Q925U4 652 73682 L481 Q L Q A P D V L F Y P L R P E
Rat Rattus norvegicus NP_001004230 576 64421 T384 A M Y L Y R A T G D P T L L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6GQB9 913 102717 T403 T Y F L Y K A T G D P Y Y L E
Zebra Danio Brachydanio rerio XP_696207 423 47287 F252 K A T G D P S F I Q L G R D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122669 600 67917 T379 V M Y L Y R A T G D P Y L I Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38888 796 91227 T421 T Y F L Y R A T K D P F Y L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.4 96.1 N.A. 37.7 94.1 N.A. N.A. N.A. 26 54.6 N.A. N.A. 53 N.A. N.A.
Protein Similarity: 100 99.6 98.9 98 N.A. 53.9 97.5 N.A. N.A. N.A. 37.9 65.7 N.A. N.A. 68.5 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 13.3 100 N.A. N.A. N.A. 60 0 N.A. N.A. 73.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 20 100 N.A. N.A. N.A. 73.3 6.6 N.A. N.A. 86.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 10 0 10 0 0 80 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 10 0 0 0 80 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70 % E
% Phe: 0 0 20 0 0 0 0 10 10 0 0 10 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 70 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % I
% Lys: 10 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 10 0 80 0 0 0 10 0 0 10 10 60 70 0 % L
% Met: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 10 10 0 0 0 0 90 0 0 10 0 % P
% Gln: 10 0 10 0 0 0 0 0 0 10 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 70 0 0 0 0 0 0 20 0 0 % R
% Ser: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % S
% Thr: 20 0 10 0 0 0 0 80 0 0 0 50 0 0 0 % T
% Val: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 20 60 0 80 0 0 0 0 10 0 20 20 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _