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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUBB2B All Species: 45.45
Human Site: S126 Identified Species: 90.91
UniProt: Q9BVA1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVA1 NP_821080.1 445 49953 S126 V V R K E S E S C D C L Q G F
Chimpanzee Pan troglodytes Q8WP14 444 49773 S126 V V R K E A E S C D C L Q G F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535868 543 59433 S224 V V R K E S E S C D C L Q G F
Cat Felis silvestris
Mouse Mus musculus Q9ERD7 450 50400 N126 V V R K E C E N C D C L Q G F
Rat Rattus norvegicus Q6P9T8 445 49782 S126 V V R K E A E S C D C L Q G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P32882 445 49935 S126 V V R K E S E S C D C L Q G F
Frog Xenopus laevis P13602 443 49705 S126 V V R K E S E S C D C L Q G F
Zebra Danio Brachydanio rerio NP_942104 445 49768 S126 V V R K E A E S C D C L Q G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24560 447 50129 S126 V V R K E A E S C D C L Q G F
Honey Bee Apis mellifera XP_392313 447 50157 S126 V V R K E A E S C D C L Q G F
Nematode Worm Caenorhab. elegans P41937 444 49782 S126 V V R K E A E S C D C L Q G F
Sea Urchin Strong. purpuratus XP_791790 447 50098 S126 V V R K E A E S C D C L Q G F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.8 N.A. 79.9 N.A. 91.1 96.6 N.A. N.A. 99.5 98.8 96.6 N.A. 95.7 95.5 93.2 96.6
Protein Similarity: 100 94.6 N.A. 80.6 N.A. 95.7 98.8 N.A. N.A. 99.5 99.5 99 N.A. 97.9 98.2 98.1 98.8
P-Site Identity: 100 93.3 N.A. 100 N.A. 86.6 93.3 N.A. N.A. 100 100 93.3 N.A. 93.3 93.3 93.3 93.3
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 100 N.A. N.A. 100 100 100 N.A. 100 100 100 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 100 0 100 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % D
% Glu: 0 0 0 0 100 0 100 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % Q
% Arg: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 34 0 92 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 100 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _