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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DSCC1
All Species:
32.12
Human Site:
S175
Identified Species:
64.24
UniProt:
Q9BVC3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVC3
NP_076999.2
393
44825
S175
L
L
D
Q
I
Q
A
S
E
E
E
I
M
T
Q
Chimpanzee
Pan troglodytes
XP_519925
334
37976
D151
E
N
P
Y
E
G
P
D
S
Q
K
E
K
D
S
Rhesus Macaque
Macaca mulatta
XP_001097551
393
44773
S175
L
L
D
Q
I
Q
A
S
E
E
E
I
M
T
Q
Dog
Lupus familis
XP_851311
392
44918
S174
L
L
D
Q
I
Q
A
S
E
E
E
I
M
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q14AI0
399
45503
S181
L
L
N
H
I
Q
A
S
E
E
E
I
M
A
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506519
196
22903
S13
F
F
D
Q
V
Q
A
S
E
E
E
I
L
A
Q
Chicken
Gallus gallus
XP_418464
389
44024
S171
L
L
S
L
I
Q
A
S
E
E
E
I
L
H
Q
Frog
Xenopus laevis
Q6GMB0
390
44536
S172
L
L
S
V
I
Q
S
S
T
E
E
L
M
D
H
Zebra Danio
Brachydanio rerio
Q66I84
391
44637
S171
L
L
E
R
I
Q
A
S
K
E
E
L
E
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611466
425
48765
S211
L
L
D
T
V
Q
C
S
R
G
Q
F
M
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196466
224
26218
E41
H
I
L
S
L
V
Q
E
N
S
W
S
Y
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001136493
403
44399
S186
L
C
K
L
I
Q
A
S
D
G
E
L
L
D
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.2
97.7
92.6
N.A.
84.4
N.A.
N.A.
43.5
77.8
70.4
67.1
N.A.
27.5
N.A.
N.A.
27.9
Protein Similarity:
100
84.4
98.7
95.4
N.A.
89.7
N.A.
N.A.
46
87
82.4
83.2
N.A.
48.2
N.A.
N.A.
40.4
P-Site Identity:
100
0
100
100
N.A.
80
N.A.
N.A.
66.6
73.3
53.3
53.3
N.A.
40
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
100
N.A.
86.6
N.A.
N.A.
80
80
66.6
80
N.A.
53.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
29.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
43.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
60
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
67
0
0
0
0
0
0
25
9
% A
% Cys:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
42
0
0
0
0
9
9
0
0
0
0
34
0
% D
% Glu:
9
0
9
0
9
0
0
9
50
67
75
9
9
9
9
% E
% Phe:
9
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
17
0
0
0
0
9
% G
% His:
9
0
0
9
0
0
0
0
0
0
0
0
0
9
17
% H
% Ile:
0
9
0
0
67
0
0
0
0
0
0
50
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
9
0
9
0
9
0
0
% K
% Leu:
75
67
9
17
9
0
0
0
0
0
0
25
25
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% M
% Asn:
0
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
34
0
84
9
0
0
9
9
0
0
0
50
% Q
% Arg:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
17
9
0
0
9
84
9
9
0
9
0
0
9
% S
% Thr:
0
0
0
9
0
0
0
0
9
0
0
0
0
25
0
% T
% Val:
0
0
0
9
17
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _