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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DSCC1
All Species:
21.52
Human Site:
S220
Identified Species:
43.03
UniProt:
Q9BVC3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVC3
NP_076999.2
393
44825
S220
L
V
D
S
E
S
W
S
F
G
K
V
P
L
N
Chimpanzee
Pan troglodytes
XP_519925
334
37976
R196
C
K
I
G
G
Y
W
R
I
L
E
F
D
Y
E
Rhesus Macaque
Macaca mulatta
XP_001097551
393
44773
S220
L
V
D
S
E
S
W
S
F
S
K
V
P
L
N
Dog
Lupus familis
XP_851311
392
44918
S219
L
V
D
S
E
S
W
S
F
D
K
V
P
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q14AI0
399
45503
S226
L
V
D
S
E
S
W
S
L
D
R
V
P
L
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506519
196
22903
P58
L
V
D
S
E
S
W
P
F
N
K
V
P
L
R
Chicken
Gallus gallus
XP_418464
389
44024
P216
L
I
D
S
E
S
W
P
F
N
K
V
P
L
R
Frog
Xenopus laevis
Q6GMB0
390
44536
S217
L
I
D
S
E
S
W
S
F
S
K
V
P
L
Q
Zebra Danio
Brachydanio rerio
Q66I84
391
44637
S216
L
V
D
S
E
S
W
S
F
S
K
V
P
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611466
425
48765
A256
L
I
S
E
N
S
W
A
L
D
E
V
E
R
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196466
224
26218
S86
R
G
K
N
D
D
G
S
E
E
A
M
Y
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001136493
403
44399
P231
N
S
V
L
R
D
W
P
L
K
A
M
P
E
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.2
97.7
92.6
N.A.
84.4
N.A.
N.A.
43.5
77.8
70.4
67.1
N.A.
27.5
N.A.
N.A.
27.9
Protein Similarity:
100
84.4
98.7
95.4
N.A.
89.7
N.A.
N.A.
46
87
82.4
83.2
N.A.
48.2
N.A.
N.A.
40.4
P-Site Identity:
100
6.6
93.3
93.3
N.A.
73.3
N.A.
N.A.
80
73.3
80
86.6
N.A.
26.6
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
80
N.A.
N.A.
80
80
86.6
93.3
N.A.
46.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
29.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
43.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
17
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
67
0
9
17
0
0
0
25
0
0
9
0
0
% D
% Glu:
0
0
0
9
67
0
0
0
9
9
17
0
9
9
17
% E
% Phe:
0
0
0
0
0
0
0
0
59
0
0
9
0
0
0
% F
% Gly:
0
9
0
9
9
0
9
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
9
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
9
9
0
0
0
0
0
0
9
59
0
0
0
0
% K
% Leu:
75
0
0
9
0
0
0
0
25
9
0
0
0
67
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% M
% Asn:
9
0
0
9
9
0
0
0
0
17
0
0
0
0
25
% N
% Pro:
0
0
0
0
0
0
0
25
0
0
0
0
75
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
9
0
0
0
9
0
0
9
0
0
9
0
0
9
17
% R
% Ser:
0
9
9
67
0
75
0
59
0
25
0
0
0
9
17
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
50
9
0
0
0
0
0
0
0
0
75
0
0
0
% V
% Trp:
0
0
0
0
0
0
92
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _