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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DSCC1
All Species:
16.97
Human Site:
Y253
Identified Species:
33.94
UniProt:
Q9BVC3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVC3
NP_076999.2
393
44825
Y253
L
K
C
Y
G
K
K
Y
V
D
E
G
E
V
Y
Chimpanzee
Pan troglodytes
XP_519925
334
37976
K223
S
E
S
W
S
F
S
K
V
P
L
N
T
C
L
Rhesus Macaque
Macaca mulatta
XP_001097551
393
44773
Y253
L
K
C
Y
G
K
K
Y
V
D
E
G
E
V
Y
Dog
Lupus familis
XP_851311
392
44918
Y252
L
K
C
Y
G
K
K
Y
I
E
E
G
E
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q14AI0
399
45503
Y259
L
K
C
Y
G
K
R
Y
V
D
K
D
D
V
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506519
196
22903
E85
E
M
I
Q
H
C
L
E
C
Y
G
K
K
Y
T
Chicken
Gallus gallus
XP_418464
389
44024
Y249
L
S
S
Y
G
R
K
Y
S
D
D
G
E
V
Y
Frog
Xenopus laevis
Q6GMB0
390
44536
L250
L
T
C
Y
G
K
R
L
M
E
E
G
G
D
C
Zebra Danio
Brachydanio rerio
Q66I84
391
44637
H249
L
N
C
Y
G
R
R
H
S
D
E
D
N
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611466
425
48765
E297
E
R
C
P
G
K
F
E
Y
Q
E
S
L
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196466
224
26218
F113
L
L
R
P
A
D
K
F
N
L
T
E
F
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001136493
403
44399
V265
L
N
R
F
G
T
K
V
E
Q
E
A
R
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.2
97.7
92.6
N.A.
84.4
N.A.
N.A.
43.5
77.8
70.4
67.1
N.A.
27.5
N.A.
N.A.
27.9
Protein Similarity:
100
84.4
98.7
95.4
N.A.
89.7
N.A.
N.A.
46
87
82.4
83.2
N.A.
48.2
N.A.
N.A.
40.4
P-Site Identity:
100
6.6
100
86.6
N.A.
73.3
N.A.
N.A.
0
66.6
46.6
40
N.A.
33.3
N.A.
N.A.
13.3
P-Site Similarity:
100
20
100
100
N.A.
93.3
N.A.
N.A.
6.6
80
66.6
60
N.A.
40
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
29.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
43.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
59
0
0
9
0
0
9
0
0
0
0
9
9
% C
% Asp:
0
0
0
0
0
9
0
0
0
42
9
17
9
9
0
% D
% Glu:
17
9
0
0
0
0
0
17
9
17
59
9
34
0
9
% E
% Phe:
0
0
0
9
0
9
9
9
0
0
0
0
9
0
9
% F
% Gly:
0
0
0
0
75
0
0
0
0
0
9
42
9
0
0
% G
% His:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
34
0
0
0
50
50
9
0
0
9
9
9
0
0
% K
% Leu:
75
9
0
0
0
0
9
9
0
9
9
0
9
9
9
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
0
9
0
0
9
9
0
0
% N
% Pro:
0
0
0
17
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
17
0
0
0
9
0
% Q
% Arg:
0
9
17
0
0
17
25
0
0
0
0
0
9
0
0
% R
% Ser:
9
9
17
0
9
0
9
0
17
0
0
9
0
9
9
% S
% Thr:
0
9
0
0
0
9
0
0
0
0
9
0
9
0
9
% T
% Val:
0
0
0
0
0
0
0
9
34
0
0
0
0
50
9
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
59
0
0
0
42
9
9
0
0
0
9
42
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _