KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLST8
All Species:
46.36
Human Site:
S289
Identified Species:
78.46
UniProt:
Q9BVC4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVC4
NP_071767.3
326
35876
S289
S
Q
Y
I
V
T
A
S
S
D
N
L
A
R
L
Chimpanzee
Pan troglodytes
XP_510741
398
43440
S361
S
Q
Y
I
V
T
A
S
S
D
N
L
A
R
L
Rhesus Macaque
Macaca mulatta
XP_001084050
350
38071
A312
P
A
Q
S
P
P
P
A
S
S
D
N
L
A
R
Dog
Lupus familis
XP_853618
326
35875
S289
S
Q
Y
I
V
T
A
S
S
D
N
L
A
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCJ1
326
35833
S289
S
Q
Y
I
V
T
A
S
S
D
N
L
A
R
L
Rat
Rattus norvegicus
Q9Z2K5
326
35925
S289
S
Q
Y
I
V
T
A
S
S
D
N
L
A
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514926
186
20314
S150
Q
Y
I
V
T
G
S
S
D
N
L
A
R
L
W
Chicken
Gallus gallus
XP_414858
326
36074
S289
S
Q
Y
I
V
T
A
S
S
D
N
L
A
R
L
Frog
Xenopus laevis
Q6PA72
326
36099
S289
S
Q
Y
I
V
T
A
S
S
D
N
L
A
R
L
Zebra Danio
Brachydanio rerio
Q803V5
326
36193
S289
S
Q
Y
I
V
T
A
S
S
D
N
L
A
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W328
313
35328
S275
S
K
W
L
F
T
A
S
S
D
G
I
A
R
L
Honey Bee
Apis mellifera
XP_393223
320
35675
S281
S
Q
Y
I
F
T
A
S
S
D
G
V
A
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786340
315
35177
S278
S
Q
Y
V
V
T
A
S
S
D
R
T
A
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41318
303
34015
T267
A
D
S
A
Y
L
V
T
A
S
S
D
H
Y
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
87.7
99
N.A.
97.8
96.9
N.A.
53
93.8
91
92.3
N.A.
48.7
65.3
N.A.
64.4
Protein Similarity:
100
81.6
88.8
99.6
N.A.
99
98.1
N.A.
54.9
96.9
96
96.3
N.A.
67.4
80.9
N.A.
80
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
60
80
N.A.
80
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
86.6
86.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
47.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
0
79
8
8
0
0
8
79
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
8
79
8
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
8
65
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
8
0
0
0
0
8
58
8
8
79
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
58
8
0
0
0
% N
% Pro:
8
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
8
72
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
8
79
8
% R
% Ser:
79
0
8
8
0
0
8
86
86
15
8
0
0
0
0
% S
% Thr:
0
0
0
0
8
79
0
8
0
0
0
8
0
0
0
% T
% Val:
0
0
0
15
65
0
8
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
72
0
8
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _