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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLST8
All Species:
35.45
Human Site:
Y184
Identified Species:
60
UniProt:
Q9BVC4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVC4
NP_071767.3
326
35876
Y184
H
I
D
P
D
A
S
Y
M
A
A
V
N
S
T
Chimpanzee
Pan troglodytes
XP_510741
398
43440
Y256
H
I
D
P
D
A
S
Y
M
A
A
V
N
S
T
Rhesus Macaque
Macaca mulatta
XP_001084050
350
38071
Y207
H
I
D
P
D
A
S
Y
M
A
A
V
N
S
A
Dog
Lupus familis
XP_853618
326
35875
Y184
H
I
D
P
D
A
S
Y
M
A
A
V
N
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCJ1
326
35833
Y184
H
I
D
P
D
A
S
Y
M
A
A
V
N
S
A
Rat
Rattus norvegicus
Q9Z2K5
326
35925
Y184
H
I
D
P
D
A
S
Y
M
A
A
V
N
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514926
186
20314
M45
I
D
P
D
A
S
Y
M
A
A
V
N
S
S
G
Chicken
Gallus gallus
XP_414858
326
36074
Y184
H
I
D
P
D
A
S
Y
M
A
A
V
N
S
S
Frog
Xenopus laevis
Q6PA72
326
36099
Y184
H
I
D
P
D
A
S
Y
M
A
A
V
N
S
S
Zebra Danio
Brachydanio rerio
Q803V5
326
36193
Y184
H
I
D
P
D
A
S
Y
M
A
A
V
N
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W328
313
35328
D170
E
V
D
A
S
I
Q
D
V
A
I
S
P
D
G
Honey Bee
Apis mellifera
XP_393223
320
35675
A176
E
A
S
V
Q
D
V
A
I
D
Q
D
G
T
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786340
315
35177
I173
S
S
I
Q
S
I
A
I
D
P
E
A
T
H
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41318
303
34015
L162
T
P
E
D
D
T
S
L
Q
S
L
S
M
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
87.7
99
N.A.
97.8
96.9
N.A.
53
93.8
91
92.3
N.A.
48.7
65.3
N.A.
64.4
Protein Similarity:
100
81.6
88.8
99.6
N.A.
99
98.1
N.A.
54.9
96.9
96
96.3
N.A.
67.4
80.9
N.A.
80
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
13.3
93.3
93.3
93.3
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
26.6
100
100
100
N.A.
26.6
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
47.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
65
8
8
8
79
65
8
0
8
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
72
15
72
8
0
8
8
8
0
8
0
8
0
% D
% Glu:
15
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
15
% G
% His:
65
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
65
8
0
0
15
0
8
8
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
65
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
65
0
0
% N
% Pro:
0
8
8
65
0
0
0
0
0
8
0
0
8
0
0
% P
% Gln:
0
0
0
8
8
0
8
0
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
8
0
15
8
72
0
0
8
0
15
8
72
29
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
0
0
8
8
22
% T
% Val:
0
8
0
8
0
0
8
0
8
0
8
65
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
65
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _