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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLST8
All Species:
31.21
Human Site:
Y222
Identified Species:
52.82
UniProt:
Q9BVC4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVC4
NP_071767.3
326
35876
Y222
K
I
P
A
H
T
R
Y
A
L
Q
C
R
F
S
Chimpanzee
Pan troglodytes
XP_510741
398
43440
Y294
K
I
P
A
H
T
R
Y
A
L
Q
C
R
F
S
Rhesus Macaque
Macaca mulatta
XP_001084050
350
38071
Y245
K
I
P
A
H
T
R
Y
A
L
Q
C
R
F
S
Dog
Lupus familis
XP_853618
326
35875
Y222
K
I
P
A
H
T
R
Y
A
L
Q
C
R
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCJ1
326
35833
Y222
K
I
P
A
H
T
R
Y
A
L
Q
C
R
F
S
Rat
Rattus norvegicus
Q9Z2K5
326
35925
Y222
K
I
P
A
H
T
R
Y
A
L
Q
C
R
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514926
186
20314
A83
I
P
A
H
N
R
Y
A
L
Q
C
K
F
S
P
Chicken
Gallus gallus
XP_414858
326
36074
Y222
K
I
P
A
H
N
R
Y
A
L
Q
C
K
F
S
Frog
Xenopus laevis
Q6PA72
326
36099
C222
K
I
P
A
H
K
R
C
A
L
K
C
K
F
S
Zebra Danio
Brachydanio rerio
Q803V5
326
36193
Y222
K
I
P
A
H
K
R
Y
S
L
R
C
K
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W328
313
35328
R208
M
S
T
L
R
P
N
R
K
I
P
A
H
S
R
Honey Bee
Apis mellifera
XP_393223
320
35675
K214
T
R
L
N
P
R
H
K
L
S
A
H
K
R
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786340
315
35177
K211
S
Q
L
H
P
K
T
K
I
P
A
H
K
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41318
303
34015
V200
D
A
S
H
L
K
P
V
T
K
F
R
A
H
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
87.7
99
N.A.
97.8
96.9
N.A.
53
93.8
91
92.3
N.A.
48.7
65.3
N.A.
64.4
Protein Similarity:
100
81.6
88.8
99.6
N.A.
99
98.1
N.A.
54.9
96.9
96
96.3
N.A.
67.4
80.9
N.A.
80
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
86.6
73.3
73.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
93.3
86.6
93.3
N.A.
6.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
47.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
65
0
0
0
8
58
0
15
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
65
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
8
65
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
22
65
0
8
0
0
0
0
15
8
8
0
% H
% Ile:
8
65
0
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
65
0
0
0
0
29
0
15
8
8
8
8
36
8
0
% K
% Leu:
0
0
15
8
8
0
0
0
15
65
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
65
0
15
8
8
0
0
8
8
0
0
0
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
8
50
0
0
0
0
% Q
% Arg:
0
8
0
0
8
15
65
8
0
0
8
8
43
8
8
% R
% Ser:
8
8
8
0
0
0
0
0
8
8
0
0
0
15
72
% S
% Thr:
8
0
8
0
0
43
8
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
58
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _