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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLST8
All Species:
36.36
Human Site:
Y62
Identified Species:
61.54
UniProt:
Q9BVC4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVC4
NP_071767.3
326
35876
Y62
S
M
I
A
A
A
G
Y
Q
H
I
R
M
Y
D
Chimpanzee
Pan troglodytes
XP_510741
398
43440
Y134
S
M
I
A
A
A
G
Y
Q
H
I
R
M
Y
D
Rhesus Macaque
Macaca mulatta
XP_001084050
350
38071
Y85
S
M
I
A
A
A
G
Y
Q
H
I
R
M
Y
D
Dog
Lupus familis
XP_853618
326
35875
Y62
S
M
I
A
A
A
G
Y
Q
H
I
R
M
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCJ1
326
35833
Y62
S
M
I
A
A
A
G
Y
Q
H
I
R
M
Y
D
Rat
Rattus norvegicus
Q9Z2K5
326
35925
Y62
S
M
I
A
A
T
G
Y
Q
H
I
R
M
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514926
186
20314
Chicken
Gallus gallus
XP_414858
326
36074
Y62
S
M
I
A
A
A
G
Y
Q
H
I
R
M
Y
D
Frog
Xenopus laevis
Q6PA72
326
36099
Y62
S
M
I
A
A
A
G
Y
Q
H
I
R
M
Y
D
Zebra Danio
Brachydanio rerio
Q803V5
326
36193
Y62
S
M
I
A
A
A
G
Y
Q
H
I
R
M
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W328
313
35328
E66
C
I
R
L
Y
D
L
E
S
N
C
T
A
P
V
Honey Bee
Apis mellifera
XP_393223
320
35675
I64
A
A
A
G
Y
Q
H
I
R
M
Y
D
L
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786340
315
35177
D69
M
Y
D
I
N
S
G
D
T
T
P
I
I
N
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41318
303
34015
Y58
G
H
Q
N
V
R
L
Y
D
I
R
T
T
N
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
87.7
99
N.A.
97.8
96.9
N.A.
53
93.8
91
92.3
N.A.
48.7
65.3
N.A.
64.4
Protein Similarity:
100
81.6
88.8
99.6
N.A.
99
98.1
N.A.
54.9
96.9
96
96.3
N.A.
67.4
80.9
N.A.
80
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
0
100
100
100
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
0
100
100
100
N.A.
13.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
47.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
65
65
58
0
0
0
0
0
0
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
8
8
0
0
8
0
0
65
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
72
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
65
0
0
0
0
0
% H
% Ile:
0
8
65
8
0
0
0
8
0
8
65
8
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
15
0
0
0
0
0
8
0
0
% L
% Met:
8
65
0
0
0
0
0
0
0
8
0
0
65
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
8
0
0
0
15
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% P
% Gln:
0
0
8
0
0
8
0
0
65
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
0
8
0
8
65
0
0
0
% R
% Ser:
65
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
8
0
0
8
8
0
15
8
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
15
0
0
72
0
0
8
0
0
65
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _