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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG8 All Species: 26.06
Human Site: S232 Identified Species: 38.22
UniProt: Q9BVK2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVK2 NP_076984.2 526 60088 S232 D G S I R W K S F S F V R V I
Chimpanzee Pan troglodytes XP_508663 559 63457 S265 D G S I R W K S F S F V R V I
Rhesus Macaque Macaca mulatta XP_001093123 526 60235 S232 D G S I R W N S F S F V R V I
Dog Lupus familis XP_533998 526 59901 S232 D G S I R W N S F S F I R L I
Cat Felis silvestris
Mouse Mus musculus Q6P8H8 526 59502 S232 D G S V R W S S F S V V R V T
Rat Rattus norvegicus Q3T1L5 507 57929 K226 F K K G L R G K G S A L F I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q802T2 507 57419 K226 F K K G L K G K G L L L L I K
Frog Xenopus laevis NP_001084808 545 61356 S250 D G S V R W R S F S C L R L V
Zebra Danio Brachydanio rerio NP_001017647 524 59437 S229 D G S L S W R S F S V L R L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W3V8 511 57926 V218 V S A V G A V V K L L V V G L
Honey Bee Apis mellifera XP_624229 524 60930 L238 N G S F F R R L F V L G G I V
Nematode Worm Caenorhab. elegans P52887 758 85848 T225 G N V L L A N T P K A I S L A
Sea Urchin Strong. purpuratus XP_786628 487 54909 M209 S F G P F I A M D Q L P Q V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80505 418 47956 I140 N L I C A L V I W S P G L L I
Baker's Yeast Sacchar. cerevisiae P40351 577 67367 L259 F K S Y K D F L F L I R W A N
Red Bread Mold Neurospora crassa Q7RXP5 504 57300 R218 L S P R S I F R I Q F F N C V
Conservation
Percent
Protein Identity: 100 93.9 97.9 92.9 N.A. 90.1 25.2 N.A. N.A. 26.6 68.4 68.4 N.A. 49.6 49.6 27 42
Protein Similarity: 100 94 98.2 95.8 N.A. 94.1 42 N.A. N.A. 43.9 82.1 82.5 N.A. 65.2 65.2 41.1 58.1
P-Site Identity: 100 100 93.3 80 N.A. 73.3 6.6 N.A. N.A. 0 60 53.3 N.A. 6.6 20 0 6.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 80 20 N.A. N.A. 13.3 93.3 86.6 N.A. 26.6 46.6 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 38.5 38.9 41.8
Protein Similarity: N.A. N.A. N.A. 51.7 56.8 57.7
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 33.3 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 13 7 0 0 0 13 0 0 7 7 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 7 0 0 7 0 % C
% Asp: 44 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 19 7 0 7 13 0 13 0 57 0 32 7 7 0 0 % F
% Gly: 7 50 7 13 7 0 13 0 13 0 0 13 7 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 25 0 13 0 7 7 0 7 13 0 19 32 % I
% Lys: 0 19 13 0 7 7 13 13 7 7 0 0 0 0 7 % K
% Leu: 7 7 0 13 19 7 0 13 0 19 25 25 13 32 13 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 13 7 0 0 0 0 19 0 0 0 0 0 7 0 7 % N
% Pro: 0 0 7 7 0 0 0 0 7 0 7 7 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 13 0 0 7 0 0 % Q
% Arg: 0 0 0 7 38 13 19 7 0 0 0 7 44 0 7 % R
% Ser: 7 13 57 0 13 0 7 44 0 57 0 0 7 0 0 % S
% Thr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % T
% Val: 7 0 7 19 0 0 13 7 0 7 13 32 7 32 25 % V
% Trp: 0 0 0 0 0 44 0 0 7 0 0 0 7 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _