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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG8 All Species: 22.12
Human Site: Y84 Identified Species: 32.44
UniProt: Q9BVK2 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVK2 NP_076984.2 526 60088 Y84 I L S H V A K Y F D Q E M L N
Chimpanzee Pan troglodytes XP_508663 559 63457 Y117 I L S H V A K Y F D Q E M L N
Rhesus Macaque Macaca mulatta XP_001093123 526 60235 Y84 I L S H V A K Y F D Q E M L N
Dog Lupus familis XP_533998 526 59901 Y84 A L S H V A K Y F D Q E M L N
Cat Felis silvestris
Mouse Mus musculus Q6P8H8 526 59502 Y84 A L S H I A K Y F D Q E M L N
Rat Rattus norvegicus Q3T1L5 507 57929 F89 L C A Y V A K F I N P D W V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q802T2 507 57419 L89 L C A Y V A K L I N P D W I A
Frog Xenopus laevis NP_001084808 545 61356 Y102 V L A K V A H Y V D P E M L K
Zebra Danio Brachydanio rerio NP_001017647 524 59437 D84 S H I A R F F D K E M L V V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W3V8 511 57926 Y88 L V V D N L N Y E S K A T V Y
Honey Bee Apis mellifera XP_624229 524 60930 F104 F L S H I A R F I D H D M L K
Nematode Worm Caenorhab. elegans P52887 758 85848 V85 F G F D E C L V I S K T P R F
Sea Urchin Strong. purpuratus XP_786628 487 54909 E80 V I K Q R R L E A E R V A S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80505 418 47956 L11 R E K S D R R L L L W F F A V
Baker's Yeast Sacchar. cerevisiae P40351 577 67367 K114 F L S Q F V P K S V R D D G C
Red Bread Mold Neurospora crassa Q7RXP5 504 57300 L89 A M I W V H N L E Y D S W Q T
Conservation
Percent
Protein Identity: 100 93.9 97.9 92.9 N.A. 90.1 25.2 N.A. N.A. 26.6 68.4 68.4 N.A. 49.6 49.6 27 42
Protein Similarity: 100 94 98.2 95.8 N.A. 94.1 42 N.A. N.A. 43.9 82.1 82.5 N.A. 65.2 65.2 41.1 58.1
P-Site Identity: 100 100 100 93.3 N.A. 86.6 20 N.A. N.A. 20 53.3 0 N.A. 6.6 46.6 0 0
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 66.6 N.A. N.A. 60 66.6 20 N.A. 33.3 73.3 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 38.5 38.9 41.8
Protein Similarity: N.A. N.A. N.A. 51.7 56.8 57.7
P-Site Identity: N.A. N.A. N.A. 0 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 19 7 0 57 0 0 7 0 0 7 7 7 13 % A
% Cys: 0 13 0 0 0 7 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 0 13 7 0 0 7 0 44 7 25 7 0 0 % D
% Glu: 0 7 0 0 7 0 0 7 13 13 0 38 0 0 7 % E
% Phe: 19 0 7 0 7 7 7 13 32 0 0 7 7 0 7 % F
% Gly: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % G
% His: 0 7 0 38 0 7 7 0 0 0 7 0 0 0 0 % H
% Ile: 19 7 13 0 13 0 0 0 25 0 0 0 0 7 0 % I
% Lys: 0 0 13 7 0 0 44 7 7 0 13 0 0 0 13 % K
% Leu: 19 50 0 0 0 7 13 19 7 7 0 7 0 44 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 7 0 44 0 0 % M
% Asn: 0 0 0 0 7 0 13 0 0 13 0 0 0 0 32 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 19 0 7 0 7 % P
% Gln: 0 0 0 13 0 0 0 0 0 0 32 0 0 7 0 % Q
% Arg: 7 0 0 0 13 13 13 0 0 0 13 0 0 7 0 % R
% Ser: 7 0 44 7 0 0 0 0 7 13 0 7 0 7 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 7 % T
% Val: 13 7 7 0 50 7 0 7 7 7 0 7 7 19 7 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 7 0 19 0 0 % W
% Tyr: 0 0 0 13 0 0 0 44 0 7 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _