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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMED9 All Species: 30.61
Human Site: T109 Identified Species: 51.79
UniProt: Q9BVK6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVK6 NP_059980.2 235 27277 T109 Y G S E G R F T F T S H T P G
Chimpanzee Pan troglodytes XP_001145723 236 27372 T110 Y G S E G R F T F T S H T P G
Rhesus Macaque Macaca mulatta XP_001093724 235 27289 T109 Y G S E G R F T F T S H T P G
Dog Lupus familis XP_538565 235 27035 T109 Y G S E G R F T F T S H T P G
Cat Felis silvestris
Mouse Mus musculus Q99KF1 235 27109 T109 Y G S E G R F T F T S H T P G
Rat Rattus norvegicus Q63584 219 24839 A96 D A T K G K F A F T T E D Y D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001086296 228 26479 T102 Y G S E G R F T F T S H T P G
Zebra Danio Brachydanio rerio NP_001002134 220 25556 T94 Y G S D G R F T F T S H T P G
Tiger Blowfish Takifugu rubipres Q90515 213 24635 Y96 F A F T T E D Y D M F E V C F
Fruit Fly Dros. melanogaster Q9I7K5 216 25140 H96 G R I S F T S H T P G E H V I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_507861 211 24505 V97 S N T P G E H V I C I Y S N S
Sea Urchin Strong. purpuratus XP_784509 218 25564 T97 R F T F T S H T P G E H T L C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05359 219 24705 T97 G S A S G D L T F L A S D S G
Red Bread Mold Neurospora crassa Q9HEK4 215 24521 H94 Q R I V F T S H H D A A F D V
Conservation
Percent
Protein Identity: 100 98.7 98.7 94 N.A. 93.6 30.6 N.A. N.A. N.A. 74 75.3 29.3 60.8 N.A. 63.4 66.3
Protein Similarity: 100 99.5 99.5 95.7 N.A. 94.4 51.9 N.A. N.A. N.A. 82.5 83.8 47.6 75.7 N.A. 74 80.8
P-Site Identity: 100 100 100 100 N.A. 100 26.6 N.A. N.A. N.A. 100 93.3 0 0 N.A. 6.6 20
P-Site Similarity: 100 100 100 100 N.A. 100 53.3 N.A. N.A. N.A. 100 100 6.6 0 N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 27.2
Protein Similarity: N.A. N.A. N.A. N.A. 48.9 47.6
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 40 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 0 0 0 0 8 0 0 15 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 8 % C
% Asp: 8 0 0 8 0 8 8 0 8 8 0 0 15 8 8 % D
% Glu: 0 0 0 43 0 15 0 0 0 0 8 22 0 0 0 % E
% Phe: 8 8 8 8 15 0 58 0 65 0 8 0 8 0 8 % F
% Gly: 15 50 0 0 72 0 0 0 0 8 8 0 0 0 58 % G
% His: 0 0 0 0 0 0 15 15 8 0 0 58 8 0 0 % H
% Ile: 0 0 15 0 0 0 0 0 8 0 8 0 0 0 8 % I
% Lys: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 8 0 0 8 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 8 0 0 0 0 8 8 0 0 0 50 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 15 0 0 0 50 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 8 50 15 0 8 15 0 0 0 50 8 8 8 8 % S
% Thr: 0 0 22 8 15 15 0 65 8 58 8 0 58 0 0 % T
% Val: 0 0 0 8 0 0 0 8 0 0 0 0 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 50 0 0 0 0 0 0 8 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _