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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM147 All Species: 19.7
Human Site: T164 Identified Species: 43.33
UniProt: Q9BVK8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVK8 NP_116024.1 224 25261 T164 T R Y D L Y H T F R P A V L L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_867866 153 16971 T93 T R Y D L Y H T F R P A V L L
Cat Felis silvestris
Mouse Mus musculus Q9CQG6 224 25316 T164 T R Y D L Y H T F R P A V L L
Rat Rattus norvegicus Q2TA63 224 25272 T164 T R Y D L Y H T F R P A V L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DFI2 225 25389 H166 T R Y D L P T H Y R L P V T V
Zebra Danio Brachydanio rerio Q6DGL7 225 25441 S166 T R Y D L P K S F R L P V A I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609789 227 25095 A166 T R H D L N K A L K P L V S L
Honey Bee Apis mellifera XP_392351 229 25489 S167 S R H D L K R S F V P I V V G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200658 207 23207 V147 L E S N V N L V Q H I S T A A
Poplar Tree Populus trichocarpa XP_002302451 228 25293 K167 W L R K N K P K T L I P I I Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564509 228 25290 K167 W L R K N K P K S L I P I I Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 67.8 N.A. 99.1 99.5 N.A. N.A. N.A. 77.3 77.3 N.A. 47.1 48.9 N.A. 50.8
Protein Similarity: 100 N.A. N.A. 67.8 N.A. 99.1 99.5 N.A. N.A. N.A. 89.3 88.4 N.A. 65.6 71.6 N.A. 69.2
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. N.A. N.A. 46.6 53.3 N.A. 46.6 40 N.A. 0
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. N.A. N.A. 60 66.6 N.A. 60 66.6 N.A. 20
Percent
Protein Identity: 30.7 N.A. N.A. 29.8 N.A. N.A.
Protein Similarity: 48.6 N.A. N.A. 49.5 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 37 0 19 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 73 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 55 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 19 0 0 0 37 10 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 28 10 19 19 10 % I
% Lys: 0 0 0 19 0 28 19 19 0 10 0 0 0 0 0 % K
% Leu: 10 19 0 0 73 0 10 0 10 19 19 10 0 37 46 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 19 19 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 19 19 0 0 0 55 37 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 73 19 0 0 0 10 0 0 55 0 0 0 0 0 % R
% Ser: 10 0 10 0 0 0 0 19 10 0 0 10 0 10 0 % S
% Thr: 64 0 0 0 0 0 10 37 10 0 0 0 10 10 0 % T
% Val: 0 0 0 0 10 0 0 10 0 10 0 0 73 10 10 % V
% Trp: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 55 0 0 37 0 0 10 0 0 0 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _