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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM147 All Species: 26.06
Human Site: Y21 Identified Species: 57.33
UniProt: Q9BVK8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVK8 NP_116024.1 224 25261 Y21 Y F P Y F I T Y K C S G L S E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_867866 153 16971
Cat Felis silvestris
Mouse Mus musculus Q9CQG6 224 25316 Y21 Y F P Y F I T Y K C S G L S E
Rat Rattus norvegicus Q2TA63 224 25272 Y21 Y F P Y F I T Y K C S G L S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DFI2 225 25389 Y21 Y F P Y F I T Y K C S G L S E
Zebra Danio Brachydanio rerio Q6DGL7 225 25441 Y21 Y F P Y F I T Y K C S G L S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609789 227 25095 S23 Y Y F T Y K Y S G L S E Y G A
Honey Bee Apis mellifera XP_392351 229 25489 S24 Y Y L T Y K Y S G L S E Y G A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200658 207 23207
Poplar Tree Populus trichocarpa XP_002302451 228 25293 Y21 F G P H A V Y Y S A T P L S E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564509 228 25290 Y21 F G P H A V Y Y S A T P L S E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 67.8 N.A. 99.1 99.5 N.A. N.A. N.A. 77.3 77.3 N.A. 47.1 48.9 N.A. 50.8
Protein Similarity: 100 N.A. N.A. 67.8 N.A. 99.1 99.5 N.A. N.A. N.A. 89.3 88.4 N.A. 65.6 71.6 N.A. 69.2
P-Site Identity: 100 N.A. N.A. 0 N.A. 100 100 N.A. N.A. N.A. 100 100 N.A. 13.3 13.3 N.A. 0
P-Site Similarity: 100 N.A. N.A. 0 N.A. 100 100 N.A. N.A. N.A. 100 100 N.A. 26.6 26.6 N.A. 0
Percent
Protein Identity: 30.7 N.A. N.A. 29.8 N.A. N.A.
Protein Similarity: 48.6 N.A. N.A. 49.5 N.A. N.A.
P-Site Identity: 33.3 N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: 60 N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 0 0 0 0 19 0 0 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 46 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 64 % E
% Phe: 19 46 10 0 46 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 0 0 0 0 0 0 19 0 0 46 0 19 0 % G
% His: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 46 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 19 0 0 46 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 0 0 0 19 0 0 64 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 64 0 0 0 0 0 0 0 0 19 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 19 19 0 64 0 0 64 0 % S
% Thr: 0 0 0 19 0 0 46 0 0 0 19 0 0 0 0 % T
% Val: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 64 19 0 46 19 0 37 64 0 0 0 0 19 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _