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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM147 All Species: 9.09
Human Site: Y65 Identified Species: 20
UniProt: Q9BVK8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVK8 NP_116024.1 224 25261 Y65 P T W E G G I Y D F I G E F M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_867866 153 16971
Cat Felis silvestris
Mouse Mus musculus Q9CQG6 224 25316 Y65 P T W E G G I Y D F I G E F M
Rat Rattus norvegicus Q2TA63 224 25272 Y65 P T W E G G I Y D F I G E F M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DFI2 225 25389 G65 P T W E G A A G A Y D F I G E
Zebra Danio Brachydanio rerio Q6DGL7 225 25441 G65 P T W E G G A G V Y D F V G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609789 227 25095 F67 A P S S S G E F N F F A E I L
Honey Bee Apis mellifera XP_392351 229 25489 F68 D N V G G E G F D L I G E F L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200658 207 23207 V51 F T Q L C K Y V F W G Y Y Y P
Poplar Tree Populus trichocarpa XP_002302451 228 25293 F65 K V S E N D S F D P Y Q E L L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564509 228 25290 F65 Q V S E T E V F D P Y Q E A L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 67.8 N.A. 99.1 99.5 N.A. N.A. N.A. 77.3 77.3 N.A. 47.1 48.9 N.A. 50.8
Protein Similarity: 100 N.A. N.A. 67.8 N.A. 99.1 99.5 N.A. N.A. N.A. 89.3 88.4 N.A. 65.6 71.6 N.A. 69.2
P-Site Identity: 100 N.A. N.A. 0 N.A. 100 100 N.A. N.A. N.A. 33.3 40 N.A. 20 40 N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 0 N.A. 100 100 N.A. N.A. N.A. 40 46.6 N.A. 40 53.3 N.A. 20
Percent
Protein Identity: 30.7 N.A. N.A. 29.8 N.A. N.A.
Protein Similarity: 48.6 N.A. N.A. 49.5 N.A. N.A.
P-Site Identity: 20 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 19 0 10 0 0 10 0 10 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 10 0 0 55 0 19 0 0 0 0 % D
% Glu: 0 0 0 64 0 19 10 0 0 0 0 0 64 0 19 % E
% Phe: 10 0 0 0 0 0 0 37 10 37 10 19 0 37 0 % F
% Gly: 0 0 0 10 55 46 10 19 0 0 10 37 0 19 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 28 0 0 0 37 0 10 10 0 % I
% Lys: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 10 0 0 0 10 37 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28 % M
% Asn: 0 10 0 0 10 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 46 10 0 0 0 0 0 0 0 19 0 0 0 0 10 % P
% Gln: 10 0 10 0 0 0 0 0 0 0 0 19 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 28 10 10 0 10 0 0 0 0 0 0 0 0 % S
% Thr: 0 55 0 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 19 10 0 0 0 10 10 10 0 0 0 10 0 0 % V
% Trp: 0 0 46 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 28 0 19 19 10 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _