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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNL3
All Species:
2.12
Human Site:
S252
Identified Species:
3.89
UniProt:
Q9BVP2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVP2
NP_055181.3
549
61993
S252
G
G
F
Q
E
T
C
S
K
A
I
R
V
G
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538054
649
72418
E315
G
N
Y
C
R
L
G
E
V
R
T
H
I
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI11
538
60768
G247
G
D
F
Q
Q
S
C
G
K
D
I
Q
V
G
V
Rat
Rattus norvegicus
Q811S9
538
60642
G247
G
G
F
Q
Q
S
C
G
K
G
V
Q
V
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513986
550
62236
N254
Q
N
F
C
E
T
D
N
E
T
L
H
V
G
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZX41
542
60839
N245
H
S
L
C
P
S
H
N
E
A
I
K
V
G
V
Zebra Danio
Brachydanio rerio
Q6DRP2
561
62883
E259
L
A
N
K
K
E
G
E
T
M
L
K
V
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MT06
581
65966
K265
Y
C
R
N
K
G
I
K
T
S
I
R
V
G
V
Honey Bee
Apis mellifera
XP_001119916
573
65075
K259
C
R
N
V
G
N
V
K
T
S
I
R
V
G
V
Nematode Worm
Caenorhab. elegans
Q21086
556
62320
K257
Y
C
R
N
K
D
I
K
T
S
I
R
V
G
V
Sea Urchin
Strong. purpuratus
XP_783153
454
50984
V185
L
V
L
L
L
N
K
V
D
L
V
P
R
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187361
582
65767
K251
Y
S
R
S
H
E
L
K
K
S
I
T
V
G
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SHR8
619
69125
T293
V
L
Q
K
D
H
P
T
C
A
M
R
S
S
I
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
30.8
N.A.
71.9
75
N.A.
55.6
N.A.
46.6
44.2
N.A.
33.7
37.8
31.8
35.7
Protein Similarity:
100
N.A.
N.A.
49.4
N.A.
83
85.2
N.A.
70.3
N.A.
66.3
62.9
N.A.
51.6
58.2
53
53
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
60
60
N.A.
40
N.A.
33.3
20
N.A.
33.3
33.3
33.3
0
P-Site Similarity:
100
N.A.
N.A.
26.6
N.A.
80
86.6
N.A.
60
N.A.
60
46.6
N.A.
46.6
40
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36
N.A.
21.9
Protein Similarity:
N.A.
N.A.
N.A.
54.6
N.A.
39.5
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
24
0
0
0
0
0
% A
% Cys:
8
16
0
24
0
0
24
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
8
8
0
8
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
16
16
0
16
16
0
0
0
0
8
0
% E
% Phe:
0
0
31
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
31
16
0
0
8
8
16
16
0
8
0
0
0
77
0
% G
% His:
8
0
0
0
8
8
8
0
0
0
0
16
0
0
0
% H
% Ile:
0
0
0
0
0
0
16
0
0
0
54
0
8
0
24
% I
% Lys:
0
0
0
16
24
0
8
31
31
0
0
16
0
0
0
% K
% Leu:
16
8
16
8
8
8
8
0
0
8
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
0
16
16
16
0
16
0
16
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
0
% P
% Gln:
8
0
8
24
16
0
0
0
0
0
0
16
0
0
0
% Q
% Arg:
0
8
24
0
8
0
0
0
0
8
0
39
8
8
0
% R
% Ser:
0
16
0
8
0
24
0
8
0
31
0
0
8
8
0
% S
% Thr:
0
0
0
0
0
16
0
8
31
8
8
8
0
0
0
% T
% Val:
8
8
0
8
0
0
8
8
8
0
16
0
77
0
77
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _