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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNL3 All Species: 47.88
Human Site: S269 Identified Species: 87.78
UniProt: Q9BVP2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVP2 NP_055181.3 549 61993 S269 F P N V G K S S I I N S L K Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538054 649 72418 S334 L P N V G K S S L I N S L K R
Cat Felis silvestris
Mouse Mus musculus Q8CI11 538 60768 S264 F P N V G K S S V I N S L K Q
Rat Rattus norvegicus Q811S9 538 60642 S264 F P N V G K S S I I N S L K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513986 550 62236 S271 F P S V G K S S I I N S L K K
Chicken Gallus gallus
Frog Xenopus laevis Q7ZX41 542 60839 S262 F A N V G K S S V I N S L K Q
Zebra Danio Brachydanio rerio Q6DRP2 561 62883 S276 F P N V G K S S I I N S L K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MT06 581 65966 S282 I P N V G K S S I I N S L T R
Honey Bee Apis mellifera XP_001119916 573 65075 S276 L P N V G K S S V I N S L K R
Nematode Worm Caenorhab. elegans Q21086 556 62320 S274 F P N V G K S S V I N S L K R
Sea Urchin Strong. purpuratus XP_783153 454 50984 R201 E K W L K H L R N E F P A V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_187361 582 65767 S268 L P N V G K S S L I N S L K R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SHR8 619 69125 S340 Y P N V G K S S I I N A L R G
Conservation
Percent
Protein Identity: 100 N.A. N.A. 30.8 N.A. 71.9 75 N.A. 55.6 N.A. 46.6 44.2 N.A. 33.7 37.8 31.8 35.7
Protein Similarity: 100 N.A. N.A. 49.4 N.A. 83 85.2 N.A. 70.3 N.A. 66.3 62.9 N.A. 51.6 58.2 53 53
P-Site Identity: 100 N.A. N.A. 80 N.A. 93.3 100 N.A. 86.6 N.A. 86.6 93.3 N.A. 80 80 86.6 0
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 100 100 N.A. 100 N.A. 93.3 100 N.A. 86.6 93.3 100 6.6
Percent
Protein Identity: N.A. N.A. N.A. 36 N.A. 21.9
Protein Similarity: N.A. N.A. N.A. 54.6 N.A. 39.5
P-Site Identity: N.A. N.A. N.A. 80 N.A. 73.3
P-Site Similarity: N.A. N.A. N.A. 93.3 N.A. 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 8 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % E
% Phe: 54 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 93 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 47 93 0 0 0 0 0 % I
% Lys: 0 8 0 0 8 93 0 0 0 0 0 0 0 77 8 % K
% Leu: 24 0 0 8 0 0 8 0 16 0 0 0 93 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 85 0 0 0 0 0 8 0 93 0 0 0 0 % N
% Pro: 0 85 0 0 0 0 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 39 % R
% Ser: 0 0 8 0 0 0 93 93 0 0 0 85 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 93 0 0 0 0 31 0 0 0 0 8 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _