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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNL3 All Species: 2.42
Human Site: T217 Identified Species: 4.44
UniProt: Q9BVP2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.42
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVP2 NP_055181.3 549 61993 T217 P K D K G K I T K R V K A K K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538054 649 72418 R279 H Q V K N L N R C T V P V D Q
Cat Felis silvestris
Mouse Mus musculus Q8CI11 538 60768 K215 L K N R K T F K I K K K K V V
Rat Rattus norvegicus Q811S9 538 60642 F215 L K N R K K T F K I K K K V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513986 550 62236 S216 P K D K V N P S R K K Q R D S
Chicken Gallus gallus
Frog Xenopus laevis Q7ZX41 542 60839 K210 I Q D K S E K K K K K K V P V
Zebra Danio Brachydanio rerio Q6DRP2 561 62883 Q220 L K D R T V Q Q K R Q Q R G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MT06 581 65966 R228 D Q A N R L G R R K L R E M K
Honey Bee Apis mellifera XP_001119916 573 65075 R222 D Q A K R L G R R K L G K K T
Nematode Worm Caenorhab. elegans Q21086 556 62320 R223 E Q K S N I G R F N S A I L N
Sea Urchin Strong. purpuratus XP_783153 454 50984 A154 V V I E V L D A R D P I G S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_187361 582 65767 W214 E Q R S N L G W K S S K A S K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SHR8 619 69125 D196 Y G G G L A D D D V Q E E D F
Conservation
Percent
Protein Identity: 100 N.A. N.A. 30.8 N.A. 71.9 75 N.A. 55.6 N.A. 46.6 44.2 N.A. 33.7 37.8 31.8 35.7
Protein Similarity: 100 N.A. N.A. 49.4 N.A. 83 85.2 N.A. 70.3 N.A. 66.3 62.9 N.A. 51.6 58.2 53 53
P-Site Identity: 100 N.A. N.A. 13.3 N.A. 13.3 26.6 N.A. 26.6 N.A. 26.6 26.6 N.A. 6.6 13.3 0 0
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 33.3 40 N.A. 53.3 N.A. 46.6 40 N.A. 40 40 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. 36 N.A. 21.9
Protein Similarity: N.A. N.A. N.A. 54.6 N.A. 39.5
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. 0
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 0 8 0 8 0 0 0 8 16 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 16 0 31 0 0 0 16 8 8 8 0 0 0 24 0 % D
% Glu: 16 0 0 8 0 8 0 0 0 0 0 8 16 0 0 % E
% Phe: 0 0 0 0 0 0 8 8 8 0 0 0 0 0 8 % F
% Gly: 0 8 8 8 8 0 31 0 0 0 0 8 8 8 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 0 8 8 0 8 8 0 8 8 0 0 % I
% Lys: 0 39 8 39 16 16 8 16 39 39 31 39 24 16 24 % K
% Leu: 24 0 0 0 8 39 0 0 0 0 16 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 16 8 24 8 8 0 0 8 0 0 0 0 8 % N
% Pro: 16 0 0 0 0 0 8 0 0 0 8 8 0 8 0 % P
% Gln: 0 47 0 0 0 0 8 8 0 0 16 16 0 0 8 % Q
% Arg: 0 0 8 24 16 0 0 31 31 16 0 8 16 0 8 % R
% Ser: 0 0 0 16 8 0 0 8 0 8 16 0 0 16 8 % S
% Thr: 0 0 0 0 8 8 8 8 0 8 0 0 0 0 16 % T
% Val: 8 8 8 0 16 8 0 0 0 8 16 0 16 16 24 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _