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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNL3
All Species:
4.85
Human Site:
T494
Identified Species:
8.89
UniProt:
Q9BVP2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVP2
NP_055181.3
549
61993
T494
D
K
D
S
D
Q
E
T
V
D
E
E
V
D
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538054
649
72418
V592
C
P
V
D
R
R
P
V
L
Q
K
I
M
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI11
538
60768
N483
Q
D
A
D
D
Q
E
N
G
S
G
E
R
N
A
Rat
Rattus norvegicus
Q811S9
538
60642
H483
Q
D
G
D
D
Q
E
H
V
T
G
E
K
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513986
550
62236
E495
E
D
Q
D
S
A
D
E
D
I
E
V
S
F
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZX41
542
60839
D483
N
D
G
E
E
E
E
D
M
E
E
E
E
D
D
Zebra Danio
Brachydanio rerio
Q6DRP2
561
62883
E504
D
T
T
T
N
T
D
E
P
E
A
E
S
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MT06
581
65966
L509
A
K
G
R
K
R
K
L
D
E
E
K
E
K
V
Honey Bee
Apis mellifera
XP_001119916
573
65075
T512
D
E
T
R
K
K
K
T
D
P
L
F
E
I
E
Nematode Worm
Caenorhab. elegans
Q21086
556
62320
E481
E
M
E
T
D
V
N
E
K
K
Q
T
V
T
S
Sea Urchin
Strong. purpuratus
XP_783153
454
50984
L400
E
G
A
A
K
I
I
L
Q
D
W
N
T
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187361
582
65767
S483
E
E
E
A
E
H
E
S
D
D
D
E
S
M
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SHR8
619
69125
G550
E
E
A
A
E
E
K
G
E
E
K
S
T
A
E
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
30.8
N.A.
71.9
75
N.A.
55.6
N.A.
46.6
44.2
N.A.
33.7
37.8
31.8
35.7
Protein Similarity:
100
N.A.
N.A.
49.4
N.A.
83
85.2
N.A.
70.3
N.A.
66.3
62.9
N.A.
51.6
58.2
53
53
P-Site Identity:
100
N.A.
N.A.
0
N.A.
26.6
33.3
N.A.
13.3
N.A.
26.6
13.3
N.A.
13.3
20
13.3
6.6
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
33.3
40
N.A.
26.6
N.A.
66.6
40
N.A.
40
40
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36
N.A.
21.9
Protein Similarity:
N.A.
N.A.
N.A.
54.6
N.A.
39.5
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
24
24
0
8
0
0
0
0
8
0
0
8
16
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
31
8
31
31
0
16
8
31
24
8
0
0
16
8
% D
% Glu:
39
24
16
8
24
16
39
24
8
31
31
47
24
8
31
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
8
24
0
0
0
0
8
8
0
16
0
0
8
8
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
8
0
8
0
8
8
% I
% Lys:
0
16
0
0
24
8
24
0
8
8
16
8
8
8
8
% K
% Leu:
0
0
0
0
0
0
0
16
8
0
8
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
8
8
0
% M
% Asn:
8
0
0
0
8
0
8
8
0
0
0
8
0
16
0
% N
% Pro:
0
8
0
0
0
0
8
0
8
8
0
0
0
0
0
% P
% Gln:
16
0
8
0
0
24
0
0
8
8
8
0
0
0
0
% Q
% Arg:
0
0
0
16
8
16
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
8
8
0
0
8
0
8
0
8
24
0
8
% S
% Thr:
0
8
16
16
0
8
0
16
0
8
0
8
16
8
8
% T
% Val:
0
0
8
0
0
8
0
8
16
0
0
8
16
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _